This paper analyses the possible determinants that induced Silicon Valley and First Republic Bank to Bankruptcy. We employ financial statements for a sample of Banks in line with the business core of Silicon Valley Bank. The period under assessment ranges from 2006-2022. We estimate an indicator of Bank Efficiency using the technique Data Envelopment Analysis (DEA). The latter indicator is used as the primary step to analyze failure within sample banks. According to the CAMEL model, macroeconomic variables are non-significant but relevant variables that drive failure were: Bank Efficiency, Capital adequacy, Earning ability, and Liquidity position ratio. Our study is relevant for any policy making to prevent any future bank failure.

While the number of AIDS-related deaths continues to rise, efforts have been made to transform the disease into a manageable chronic condition. HIV protease inhibitors have become central to combination therapy. As a result, these inhibitors have become a major focus of anti-HIV drug development. This research takes a data-driven approach to drug development through the use of quantitative structure-activity relationship (QSAR) analysis. A dataset of 450 anti-HIV drugs was used to construct and validate models. Using extensive validation methods and various machine learning algorithms, the results clearly showed that the "ET" regression outperformed the other models (“XGB”, “LGBM”, “DT”, “RF”, “GB”, “Bag”, and “HGB”) in terms of goodness of fit, predictivity, generalizability, and model robustness. Promising compounds were subjected to molecular docking and molecular dynamics simulation, resulting in drugs with favourable pharmacokinetic and pharmacodynamic properties that consistently interact with the therapeutic target.

This study sought to determine how CAATS, corporate governance (CG), and EIAF positively and directly influence the quality of financial reports (QFR). In addition to identifying the moderating effect of EIAF on the links between CAATS, CG and QFR in Saudi commercial banks. To this end, data was collected from 293 participants, including administrative managers, board members, internal auditors, certified public accountants, and staff members from the audit and internal audit departments as well as the accounting departments. Using structural equation modelling (SEM) via SmartPls, data was analyzed. The study showed that QFR is positively and significantly affected by CAATS, CG, and EIAF. Moreover, EIAF does not moderate the effect of CAATS and CG on QFR. Hence, this study enriches accounting literature and has implications for both practitioners and policymakers.

Products produced by manufacturing companies are always required to meet the requirements set by customers. Manufacturing companies need to maintain product quality by involving internal company components and external partners by using integrated information technology to become supply chain quality integration. All components in the supply chain flow must be committed to maintaining product quality in their respective roles. The research aims to ensure that technology information integration can impact firm performance through supply chain quality integration and resilience. Data collection on manufacturing companies in Java using purposive sampling found 162 companies that had received ISO certification. Respondents were determined to be employees at the middle management level and had worked for a minimum of 3 years. Data processing used partial least squares version 4 to answer all research hypotheses. The data processing results showed that information technology integration influenced supply chain quality integration by 0.588 and supply chain resilience by 0.523 and had no significant effect on increasing firm performance. Supply chain quality integration influences supply chain resilience by 0.288 and increases firm performance by 0.496. Lastly, Supply chain resilience has a positive and significant effect on increasing firm performance by 0.169. The research results provide a practical contribution to the company's top management in maintaining the role and function of technology information integration and the ISO system in maintaining supply chain quality integration. Theoretical contribution to enrich the theory of total quality management and supply chain management.

This short communication reports about new 5-amino-4-(1H-tetrazol-5-yl)-1,3-oxazoles which were synthesized by [3+2] cycloaddition of 2-R-5-amino-1,3-oxazole-4-carbonitriles and trimethylsilyl azide with dibutyltin oxide present. The reaction conditions provided high yields of the products, and were tolerant to some active functional fragments in the oxazole substituents (amino, amido, and hydroxy group). In the case of 2-((4-cyano-2-phenyloxazol-5-yl)amino)-N-methylacetamide the by-product (N-((1-(2-(methylamino)-2-oxoethyl)-1H-tetrazol-5-yl)(1H-tetrazol-5-yl)methyl)-benzamide) was formed together with the expected tetrazolyloxazole.

This paper describes the adaptive optimal control of the inventory production system with Weibull-distributed deterioration items. First of all, the dynamic model of the system is presented with all possible disturbances and uncertainties. Then, it is controlled using an adaptive and optimal controller. In this method, by having numerical data from the output of the system without using its dynamic equations, an LQR controller is estimated for it. This is important and practical because in physical systems under significant disturbances and fundamental uncertainties, the dynamic equations of the system will not have the former reliability; And it is possible to change the equations of motion by adding any non-linearity so that the conventional controllers will suffer an error. Finally, it is shown that due to the nature of the system and existing uncertainties, the used method has a clear advantage over other optimal control methods and their application in optimizing the inventory production system in the supply chain.

Transhipment is an important logistics strategy that helps to improve supply chain efficiency and reduce transportation costs. It enables cargo to be transported to multiple destinations using different modes of transportation, such as ships, trains, trucks, and planes. This can help to reduce the overall transportation time and cost, as well as improve inventory management and distribution. In addition to its use in logistics and transportation, transhipment can also be used in other industries such as manufacturing, where it can be used to transfer raw materials or finished products between different facilities or production lines. This research paper examines the role of transhipment in improving the efficiency of spare part delivery systems to the PMPML depots from central workshop Swargate. PMPML has 12 depots in total (including central workshop). In many industries, the supply chain for spare parts is complex, with multiple suppliers, warehouses, and service centres involved. Transhipment, or the transfer of inventory between locations, can help to reduce lead times and improve inventory availability. In this paper, we analyze the impact of transhipment on key performance metrics such as order fulfilment, inventory turnover, and transportation costs. We also discuss the challenges associated with implementing transhipment in spare part delivery systems, including coordination between different parties, data sharing, and system integration.

The purpose of this study is to propose a bundle of HRM practices. Specifically, this study segments HRM practices in non-overlapping practices to examine their role in organizational innovation. The methodological approach is a quantitative approach using a convenient sampling technique to collect valid data of 126 service sector employees across five sales and service centers. The findings of this study reveal that both commitment and innovation driven HRM practices positively impact organizational innovation. Meanwhile, the results have shown that the High Performance Work System does not impact organizational innovation. Thus, this study argues that to confront the challenges associated with an ever-evolving nature of organizations, top management must use integrative HRM strategies that can yield a cumulative effect in driving organizational innovation.

This paper analyses the impact of economic policy uncertainty at the firm level on the inconsistency of words and actions in their digital transformation. Using new quantitative indicators of the gap as well as robust models, we find that firm economic policy uncertainty can exacerbate the gap between what firms say and do about digital transformation. In light of these findings, the paper concludes that there tends to be a certain amount of digital transformation hype among listed firms.

In terms of competitors, spectators, and media interest, cricket is one of the favorite international sports. At the international level, cricket may be played in three formats: a five-day Test, a one-day International (ODI) for each squad of 50 overs, and a Twenty-Twenty (T20) for each team of 20 overs. Various online games that are based on the aforementioned cricket forms allow players to form a virtual squad of real-life players and score points based on how well they perform in real matches. A user gains better rank on the leaderboard if they get the most points in all of the contests they have participated in. Dream11 is one such online gaming platform which offers free and paid contests and thereby gamers can win some cash rewards. So users can select the eleven players and form a team. These eleven players should be selected from the two teams between which the match will be played. Additionally, these eleven players may be chosen from either one team or a combination of the two teams. To identify the eleven players for the T20 cricket format who can provide the maximum score to get the best rank in competitions, many studies employ Multi Criteria Decision Making (MCDM).In this paper, the TOPSIS method is utilized (weights of the performance factors of players are evaluated by using AHP) to determine the top eleven players.