Metal complexes of [2-(2-hydroxynaphthalen-1-ylazo)-pyridin-3-ol] are derived from 2-amino-3-hydroxypyridine and β-naphthol was synthesized and characterized by thermal, spectral and analytical tools. The ligand was reacted with Mn(II), Fe(II), Co(II), Ni(II), Cu(II) and Zn(II) in 1:2 stoichiometry. The IR spectra confirms the azo ligand coordination to metal ions via azo nitrogen and phenolic oxygen of pyridine after deprotonation. Both IR and 1HNMR spectra recorded involvement of deprotonated hydroxyl groups with proton displacement. The magnified fluorescence was shown by Mn(II) and Ni(II) complexes. None of the prepared ligands or complexes show any NLO activity with KDP as standard. The DNA cleavage and anticancerous activities done. The influence of zinc chelates on cure characteristics of rubber compounds was estimated based on rheometer measurements. The ligand and metal complexes are tested in vitro against some bacteria and fungi species. The antioxidant activities, DNA cleavage and anticancerous activities done. Ligand and its complexes catalysed cleavage of DNA.

Variety, quality, and rapid response are becoming a trend in customer requirements in the contemporary competitive markets. Thus, an increasing number of manufacturers are frequently seeking alternatives such as redesigning their fabrication scheme and outsourcing strategy to meet the client’s expectations effectively with minimum operating costs and limited in-house capacity. Inspired by the potential benefits of delay differentiation, outsourcing, and quality assurance policies in the multi-item production planning, this study explores a single-machine two-stage multi-item batch fabrication problem considering the abovementioned features. Stage one is the fabrication of all the required common parts, and stage two is manufacturing the end products. A predetermined portion of common parts is supplied by an external contractor to reduce the uptime of stage one. Both stages have imperfect in-house production processes. The defective items produced are identified, and they are either reworked or removed to ensure the quality of the finished batch. We develop a model to depict the problem explicitly. Modeling, formulation, derivation, and optimization methods assist us in deriving a cost-minimized cycle time solution. Moreover, the proposed model can analyze and expose the diverse features of the problem to help managerial decision-making. An example of this is the individual/ collective influence of postponement, outsourcing, and quality reassurance policies on the optimal cycle time solution, utilization, uptime of each stage, total system cost, and individual cost contributors.

The objective of this study was to assess the influence of strategic entrepreneurship, innovative entrepreneurship, and social capital on the overall performance of businesses by establishing a sustainable supply chain management system in private colleges in Jordan. The primary objective of the study was to examine the impact of these elements on the development of sustainable supply chain management and the overall performance of businesses. To assess the assumptions posited in this study, a total of 329 individuals were recruited as participants, and their data were subjected to analysis and discussion. The study demonstrated that the implementation of an entrepreneurship strategy, together with the adoption of creative entrepreneurial practices inside the organization, as well as the support and enhancement of social capital management, all contributed to the development of a sustainable supply chain management system and the enhancement of overall business performance. The significance of strategic entrepreneurship emerged, highlighting its encompassment of key elements such as Market Opportunity Assessment, resource allocation, and firm design. The subsequent concept that emerged was that of creative entrepreneurship, encompassing elements such as creativity and the production of ideas, willingness to take risks and engage in experimentation, as well as the ability to sense market trends and prioritize customer-centric innovation. Social capital emerged as a prominent feature, constituting the third important element. This category encompassed other subcategories, including networking and fostering relationships, trustworthiness and reputation, as well as the exchange of knowledge and facilitation of information dissemination. The results indicated the potential for enhancing overall business performance and developing a sustainable supply chain management by implementing an entrepreneurship strategy, specifically entrepreneurship innovativeness, and fostering social capital. This approach can aid employees in understanding their job responsibilities. The achievement of this objective can be facilitated through the provision of training and development opportunities for personnel.

In recent years, nano-filler-based hybrid composites have gained significant attention from the research community; The nano-filler-based hybrid composites can have potential applications in numerous sectors. Nano-fillers are bringing a leading development in material science and natural fibers-based composites. The present study considers the impact of various weight percentages of nano-titanium oxide (NTiO2) fillers (2%, 4%, and 6%) on the elastic features of novel hybridized banana-hemp fiber-reinforced epoxy composites. The proposed composite is analyzed for its elastic properties like longitudinal and transverse elastic modulus, axial Poisson's ratio, and axial shear modulus using homogenized micromechanical models, namely, Mori-Tanaka (M-T) model, Generalized self-consistent (G-SC) model and Modified Halpin-Tsai (M-HTS) model. The composite is modeled using one layer of banana fiber, one layer of NTiO2 and epoxy, and one layer of hemp fiber. All three layers of the composite are arranged in the sequence of banana fiber at 450, a layer of NTiO2 and epoxy at 00, and hemp fiber at 450. The proposed composite's vector sum deformation and strength are examined by employing the ANSYS APDL application. The results obtained in this study are compared with the experimental work mentioned in the literature. The composite reinforced with six weight% NTiO2 has the highest mechanical strength, and the modified Halpin-Tsai (M-HTS) model is the most effective in calculating the elastic features of the proposed composite. In addition to the above, the hybridization effect for the proposed composite is also estimated to analyze the tensile failure strain of banana and hemp fiber in the proposed hybrid composite structure.

A series of piperazine-based phthalimide derivatives 5 (a-l) were synthesized and extensively characterized using a variety of spectrum methods, including LC-MS, 1H-NMR, 13C-NMR, and FT-IR. All the derivatives were examined for their physicochemical, pharmacokinetic, bio-activity score, and PASS analysis. The 5e piperazine-based phthalimide derivative demonstrated promising antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) in the in vitro antibacterial studies. In comparison to streptomycin and bacitracin (10 µg/mL), the minimum inhibitory concentration of 5e against MRSA was discovered to be 45±0.15 micro g/ml. The anti-MRSA activity was validated with membrane damage studies by using SEM, and in silico docking studies were against 3VMT and 6FTB proteins of MRSA. In the toxicity study, 5e derivatives were evaluated against L6 cell lines. The results of the studies show the synthesized 2-(2-(4-((4-chlorophenyl) sulfonyl) piperazin-1-yl) ethyl) isoindoline-1,3-dione (5e) can be used for the development of anti-MRSA drugs.

The current research study aims to analyze the impact of cash holding on investment efficiency by moderating the role of corporate governance among financially distressed firms. The data for 14 years (2006-2019) is gathered from 400 companies of two Asian emerging economies (Pakistan and India). The results are obtained by applying a generalized method of moments (GMM), which postulates that corporate governance improves cash holding with investment efficiency in the Indian scenario and decreases in the Pakistani scenario. Concerning financially distressed firms, corporate governance strengthens the relationship of cash holding with investment efficiency in the Pakistani context but showing no moderating role in the Indian scenario. The results are helpful in cash management decisions to minimize the agency issue and to avail investment opportunities.

In this paper, a memory-based simulated annealing algorithm called the Dual Memory Simulated Annealing Algorithm (DMSA) is presented to solve multi-line facility layout problems. The objective is to minimize the total material handling cost. Two memory buffers and a restart mechanism are considered. Two benchmark problems were selected from the literature review papers and solved using the standard simulated annealing (SA) algorithm and the DMSA. The obtained results show that solutions provided by the DMSA algorithm are cost-effective compared to the standard SA algorithm and the other algorithms used for solving these test cases. Moreover, to further evaluate the performance of the DMSA algorithm in large scale problems, eleven test cases were selected from the benchmark library of the quadratic assignment problem (QAP). According to the results, the performance of the algorithm in finding solutions to complex problems is exemplary.

As foodborne diseases are current major health issues worldwide, food safety is a global health target. The present work has used social cognitive theory as theoretical support for examining the social and cognitive factors [outcome expectations (OE), self-regulation (SR), environmental determinants (ED), and self-efficacy (SE)] of Jordanian restaurant managers’ and supervisors’ food safety behavior (FSB). The moderator was willingness to comply (WC). Data were collected from the participants via Google Forms using purposive sampling methods. A total of 500 questionnaires were distributed, where 250 questionnaires were sent each to the Jordanian Restaurant Association (JRA, representing international and chain food restaurants in Jordan) as well as the Jordanian Union of Restaurants and Confectionary Proprietors (URCP, representing the local Jordanian restaurants). Two hundred and ninety-six completed questionnaires were returned. The hypotheses were analysed with smart partial least squares by structural equation modelling. The analysis determined that OE, SR, ED, and SE had positive impacts on FSB, while WC played a role in moderating the interlinkage among SE, OE, and FSB. To sum up, the current study as a whole also has significant theoretical and practical contributions for the practitioners in the given context.

The present paper elicits the zinc oxide nanoparticles-assisted synthesis of a new series of seven-membered 1,4-diazepine heterocyclic compounds as potent lead scaffolds. Structures of synthesized compounds were corroborated using spectroanalytical techniques viz, FT-IR, 1H, 13C NMR, Mass, and elemental analysis. Also, Field emission scanning electron microscopy (FE-SEM), Transmission electron microscopy (TEM), Energy dispersive x-ray analysis (EDAX), powder X-ray diffraction (PXRD), and Fourier transform infrared spectroscopy (FT-IR) were used to establish the structure and morphology of the synthesized nanocatalyst. The clean workup procedure, high to excellent yields, relatively short reaction times, and high atom economy are the incredible advantages associated with the protocol.

In this research, a maximal covering location problem (MCLP) with real-world constraints such as multiple types of facilities and vehicles with different setup costs is taken into account. An original mixed integer linear programming (MILP) model is constructed in order to find the optimal solution. Since the problem at hand is shown to be NP-hard, a constructive heuristic method and a meta-heuristic approach based on genetic algorithm (GA) are developed to solve the problem. To find the most effective solution technique, a set of problems of different sizes is randomly generated and solved by the proposed solution methods. Computational results demonstrate that the heuristic method is capable of producing optimal or near-optimal solutions in a rational execution time.