Metals play a crucial role in the metabolic pathways during the growth of vegetable plants. The presence of heavy metals or trace metals also takes a vital role in the nutrient quality of a vegetable. The vegetables are an inevitable part of the human diet and provide essential nutrients to maintain the normal functioning of human health and growth. The application of fertilizers and pesticides facilitates the accumulation of heavy metals by the vegetables grown in the fields. Consumption of heavy metals beyond the permissible limit along with vegetables may impact human health. Moreover, the production of nutritious food and its safety is an important aspect of the measure of any nation’s economy. Considering all these points, the present work was undertaken to analyze the heavy metal contents in the six mostly produced and consumed vegetables grown in Bodoland Territorial Region (BTR), a tribal-dominated region of the state Assam, India. The vegetables analyzed were fern leaves (Diplazium esculentum), jute leaves (Corchorus olitorius), green arum leaves (Colocasia esculenta), pointed gourd (Trichosanthes dioica), yard long bean (Vigna unguiculata ssp. Sesquipedalis) and spiny gourd (Momordica dioica). The metals analyzed were Cu, Fe, Ni, and Zn. The presence of heavy metals was detected in all the vegetable samples.

The performance of the manufacturing industry lies in the managers who hold crucial roles. In the revolution industry, data or knowledge holds an important role besides managers’ commitment to work optimally. As intrinsic factors, psychological capital is fundamental for managers’ behavior such as commitment and initiative to share knowledge that simultaneously enables managers’ performance. This research aimed to find the psychology capital’s effect on managers’ performance in manufacturing companies by taking into account sharing knowledge and organization commitment as moderation. Hypothesis testing was done by using data measured with a Likert Scale from 208 managers of a manufacturing company as a representative from each company stationed in the Indonesia Stock Exchange. The results of empirical testing using SEM Lisrel shows that psychological capital affects performance moderated by a variable such as managers’ commitment and knowledge sharing. Based on affected value, the initiative to share knowledge gives greater value to the correlation between psychological capital and managers’ performance in manufacturing companies; compared to commitment. Manufacturing practitioners should be able to facilitate a conducive climate to encourage their managers to share knowledge voluntarily so that the decision-making process and performance are better.

Application of the Molecular Electron Density Theory (MEDT) for the exploration of the [3+2] cycloaddition processes between methyl propynoate 1 and difluoromethyldiazomethane T-1, have been implemented using the DFT/B3LYP/6-311(d,p) level of theory. According to an examination of conceptual DFT indices, difluoromethyldiazomethane (T-1) participates in this reaction as a nucleophile, while methyl propynoate (1) should be considered as an electrophile. This cyclization is regiospecific, as evidenced by the activation and reaction energies, this agrees with the experiment's findings. It was discovered throughout ELF analysis that analyzed [3+2] cycloaddition is realised by a two-step mechanism. In addition, study of interactions of the products studied in this paper with the protein protease Covid-19 (PDB ID: 7R98) were carried out, by means of molecular docking study). The results indicate that the occurrence of the transfer of the proton to the nitrogen atom, increases the affinity of these products to the protein (CA32-F1 and CA32-F2).

Support vector machine (SVM) has become one of most developed methods for classification, focusing on cross-sectional analysis. However, classification of time series data is an important issue in statistics and data mining. Classification of time series data using SVMs that focus on cross-sectional data leads to improper classification, and hence, the SVM needs to be extended for handling time series dataset. As with cross-section data, the problem of imbalanced data is also common in time series data. Fuzzy method has been proven to be capable of overcoming the case of imbalanced data. In this paper, we developed a Fuzzy Support Vector Machine (FSVM) model to classify time series data with imbalanced class. The proposed method puts the fuzzy membership function on the constraint function. Through simulation studies, this research aims to assess the performance of the developed FSVM in classifying time series data. Based on the classification accuracy criteria, we prove that the proposed FSVM method outperforms the standard SVM method for the classification of multiclass time series data.

This research conducted testing on the influence of business strategy, leadership style, and internal control system (IC) on implementation of Good Government Governance (GGG) and its implication on organizational performance of Social Security Administrator for Health (known as BPJS Kesehatan). Data analysis was performed using a descriptive method, assisted by a statistical tool Structural Equation Modeling (SEM)-Lisrel. The data was tabulated from distributed and returned questionnaires from 325 deputy offices, branch offices, and service offices. The results showed that business strategy, leadership style, and the effectiveness of IC influenced the implementation of Good Government Governance. The result also provides evidence that leadership style had a positive significant influence on performance. Conversely, the business strategy and effectiveness of IC did not have a positive significant influence on BPJS performance.

This work includes the synthesis of ten heterocyclic compounds (3a-i and 4) containing pyrimidine moiety incorporated in their structures. Structure characterizations of these compounds were performed by using elemental and spectroscopic analyses. Their toxicity as potential insecticidal agents against the adults and nymphs of cowpea Aphid, Aphis craccivora Koch was evaluated. The results of this toxicological activity test revealed that a reasonable number of these compounds possess excellent toxicological activity against cowpea aphids such as compounds (3d), (3c), and (3b) with LC50 values 0.0125, 0.0134, and 0.0383 ppm, respectively. The toxicological activities of the rest of the tested compounds ranged from good to moderate against the same insects.

We conducted an initial evaluation of the effectiveness of the application of the model of capacity building for early diagnosis and treatment with PCI in STEMI patients in Nghe An to contribute to solving the problems and to be able to replicate the model. STEMI patients received PCI from 7/2018 - 8/2020 at Nghe An General Hospital. Retrospective and prospective cross-sectional study, intervention with comparison before and after intervention included 280 patients, mean age 71.9 ± 14.59 (years); men accounted for 69.3%. After implementing the model, the number of patients increased by 135%, the time of the door - the ball decreased (71.3 ± 71.8 compared to 152.29 ± 167.3 minutes), the length of hospital stays, and the mortality rate decreased significantly.

In this communication, condensation from different aromatic, aliphatic and heteroaromatic aldehydes, hydroxyl amine, and sodium azide in toluene reflux was used to produce electronically and structurally distinct tetrazoles with a range of yields 5-94%. Zn(OAc)2•2H2O (10 mol%) was used as a catalyst in the synthesis, which was eco-friendly, readily available, and affordable. The IR, NMR, and mass spectral studies were utilized in order to carry out a comprehensive characterization for all the 5-aryl tetrazole derivatives. This approach contributes to the current chemical synthesis of 5-substituted-1H-tetrazoles in an appealing and convenient manner thanks to its quick reaction times, good to exceptional yields, safe process, and straightforward workup.

The genetic algorithm (GA) is a natural selection-inspired optimization algorithm. It is a population-based search algorithm that utilizes the concept of survival of the fittest. This study creates a new crossover operator called “Stas Crossover” that is a combination of four crossover operators, including Single point crossover, Two points crossover, Arithmetic crossover, and Scattered crossover, and then presents the performance of this crossover operator. The area size and probability of Stas crossover can be adjusted.GA is used to find the optimal solution for this multi-product and multi-period aggregate production planning (APP) problem, which was used to test the algorithm, which provides optimal levels of inventory, backorders, overtime and regular production rates, and other controllable variables. According to the findings of this study, the benefit of stable crossover is that it allows for more variety in the way offspring are created and increases the opportunity for offspring to obtain good genetic information directly.

A series of new derivatives of 3-(pyrrol-4-yl)acrylamides 3a-l with the pyrrole nucleus functionalized by chlorine atoms and ester group, have been synthesized by simple preparative methods from the available esters of 5-chloro-4-formylpyrrol-3-carboxylic acids 1a-e. At first, 3-(pyrrol-4-yl)acrylic acids 2a-e were synthesized by the Knoevenagel’s reaction between malonic acid and the esters 1a-e. Then the target compounds were obtained with a high yield in the reactions between chloroanhydrides of the synthesized acrylic acids and aromatic or aliphatic amines in the boiling benzene. The structure of all obtained compounds was confirmed by elemental analysis, IR, ¹H-NMR, and ¹³C-NMR spectroscopy, and additionally checked by the mass-spectrometry. Then the antimicrobial activity of all amides was tested in vitro on some gram-positive and gram-negative bacteria and fungi. It has been found that the gram-negative bacteria are resistant against the synthesized chemicals, while the gram-positive bacteria are sensitive to the amides 3с, e, f, g, i. The highest activity against Staphylococcus aureus MR and Staphylococcus epidermidis MS was registered for the amide 3f, and the retardation area diameter for this amide was greater than that for the control drugs.