How to cite this paper
Gurunanjappa, P & Kariyappa, A. (2016). Design, synthesis and biological evaluation of 1,3,4-oxadiazoles/thiadiazoles bearing pyrazole scaffold as antimicrobial and antioxidant candidates.Current Chemistry Letters, 5(3), 109-122.
Refrences
1. Jayaroopa P. and Ajay Kumar K. (2013) Synthesis and antimicrobial activity of 4,5-dihydropyrazoline derivatives. Int. J. Pharm. Pharm. Sci., 5 (4) 431-433
2. Bekhit A. A., Ashour H. M. A., Ghany Y. S. A., Bekhit A. E. A., and Baraka A. (2008) Design and synthesis of some substituted 1H-pyrazolyl-thiazolo[4,5-d]pyrimidines as anti-inflammatory and antimicrobial agents. Eur. J. Med. Chem. 43, 456-463.
3. Girisha K. S., Kalluraya B., Narayana V., and Padmashree. (2010) Synthesis and pharmacological study of 1-acetyl/propyl-3-aryl-5-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)2-pyrazoline. Eur. J. Med. Chem. 45, 4640-4644.
4. Ajay Kumar K. and Jayaroopa P. (2013) Pyrazoles: Synthetic strategies and their pharmaceutical applications-An overview. Int. J. PharmTech Res., 5 (4) 1473-1486.
5. Pandeya S. N., Yogeeshwari P., and Stables J. P. (2000) Synthesis and anticonvulsant activity of 4-bromophenyl substituted aryl semicarbazones. Eur. J. Med. Chem. 35, 879-886.
6. Dutta S., Padhye S., Priyadarsini K. I., and Newton C. (2005) Antioxidant and antiproliferative activity of curcumin semicarbazone. Bioorg. Med. Chem. Lett. 15 (11) 2738-2744.
7. Noriko Chikaraishi Kasuga, Kiyoshi Sekino, Chisa Koumo, Nobuhiro Shimada, Motoki Ishikawa, and Kenji Nomiya. (2001) Synthesis, structural characterization and antimicrobial activities of 4- and 6-coordinate nickel(II) complexes with three thiosemicarbazones and semicarbazone ligands. J. Inorg. Bio. chem. 84, 55-65.
8. Gaonkar S. L., Rai K. M. L., and Prabhuswamy B. (2006) Synthesis and antimicrobial studies of a new series of 2-{4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}-5-substituted-1,3,4-oxadiazoles. Eur. J. Med. Chem. 41, 841-846.
9. Ajay Kumar K., Jayaroopa P., and Vasanth Kumar G. (2012) Comprehensive review on 1,3,4-oxadiazoles and their applications. Int. J. Chem. Tech. Res., 4 (4) 1782-1791.
10. Mohsen M. Aly, Yahia A. Mohamad, Khairy A. M. El-Bayouki, Wahid M. Basyouni, and Samir Y. Abbas. (2010) Synthesis of some new 4(3H)-quinazolinone-2-carboxaldehyde thiosemicarbazones and their metal complexes and a study on their anticonvulsant, analgesic, cytotoxic and antimicrobial activities. Eur. J. Med. Chem. 45, 3365-3373.
11. Antonios Kolocouris, Kostas Dimas, Christophe Pannecouque, Myriam Witvrouw, George B. Foscolos, George Stamatiou, George Fytas, Grigoris Zoidis, Nicolas Kolocouris, Graciela Andrei, Robert Snoeck, and Erik De Clercq. (2002) New 2-(-Adamantylcarbonyl)pyridine and 1-Acetyladamantane Thiosemicarbazones: Cell Growth Inhibitory, Antiviral and Antimicrobial Activity Evaluation. Bio. Med. Chem. Lett. 12, 723-727.
12. Vibha Mishra, Pandeya S. N., Christophe Pannecouque, MyriamWitvrouw, and De Clercq E. (2002) Anti-HIV Activity of Thiosemicarbazone and Semicarbazone Derivatives of (±)-3-Menthone. Arch. Pharm. 5, 183-186.
13. Wei-xiao Hu, Wei Zhou, Chun-nianXia, and Xi Wen. (2006) Synthesis and anticancer activity of thiosemicarbazones. Bioorg. Med. Chem. Lett. 16, 2213-2218.
14. Prakash Karegoudar D., Jagdeesh P., Mithun A., Manjathuru M., Boja P., and Bantwal S.H. (2008) Synthesis, antimicrobial and anti-inflammatory activities of some 1,2,4-triazolo[3,4-b][1,3,4] thiadiazoles and 1,2,4-triazolo[3,4-b][1,3,4] thiadiazines bearing trichlorophenyl moiety. Eur. J. Med. Chem., 43, 808-815.
15. Ajay Kumar K., Renuka N. and Vasanth Kumar G. (2013) Thiadiazoles: Molecules of diverse applications-A review. Int. J. Pharm. Tech. Res., 5 (1) 239-248.
16. Pavithra Gurunanjappa, Renuka Nagamallu, Ajay Kumar Kariyappa. (2015) Synthesis and antimicrobial activity of fused pyrazoles. Int. J. Pharm. Pharm. Sci. 7, 379-381.
17. Renuka N., Pavithra G. and Ajay Kumar K. (2014) Synthesis and their antioxidant activity studies of 1,4-benzothiazepine analogues. Der Pharma Chemica, 6 (1) 482-485.
18. Backman TW., Cao Y., and Girke T. (2011) ChemMine tools: an online service for analyzing and clustering small molecules Nucleic Acids Res. 39, W486-491.
19. Roy K., and Mitra I. (2011)On various metrics used for validation of predictive QSAR models with applications in virtual screening and focused library design. Comb. Chem. High Throughput Screen. 14, 450-474.
20. Renuka Nagamallu, Bharath Srinivasan, Mylarappa B Ningappa, Ajay Kumar Kariyappa. (2016) Synthesis of novel coumarin appended bis(formylpyrazole) derivatives: Studies on their antimicrobial and oxidant activities. Bioorg. Med. Chem. Lett., 26 (2) 690-694.
21. Padmaja A., Rajashekar C., Muralikrishna A., and Padmavathi V. (2011) Synthesis and antioxidant activity of oxazolyl/thiazolylsulfonylmethyl pyrazoles and isoxazoles. Eur. J. Med. Chem. 46, 5034-5038.
22. De Rojas-Walker T.D., Tamir S., Ji H., Wishnok J.S., and Tannenbaum S.R. (1995) Nitrioxide induces oxidative damage in addition to deamination in microphage DNA. Chem. Res. 8, 473-4777.
23. Paul Hochestein, and Ahead S.A. (1988) The nature of oxidants and antioxidant systems in the inhibition of mutation and cancer. Mutat. Res. 202, 363-375.
24. Emmanuel Mukwevho, Zané Ferreira and Ademola Ayeleso. (2014) Potential role of sulfur-containing antioxidant systems in highly oxidative environments. Molecules 19, 19376-19389.
2. Bekhit A. A., Ashour H. M. A., Ghany Y. S. A., Bekhit A. E. A., and Baraka A. (2008) Design and synthesis of some substituted 1H-pyrazolyl-thiazolo[4,5-d]pyrimidines as anti-inflammatory and antimicrobial agents. Eur. J. Med. Chem. 43, 456-463.
3. Girisha K. S., Kalluraya B., Narayana V., and Padmashree. (2010) Synthesis and pharmacological study of 1-acetyl/propyl-3-aryl-5-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)2-pyrazoline. Eur. J. Med. Chem. 45, 4640-4644.
4. Ajay Kumar K. and Jayaroopa P. (2013) Pyrazoles: Synthetic strategies and their pharmaceutical applications-An overview. Int. J. PharmTech Res., 5 (4) 1473-1486.
5. Pandeya S. N., Yogeeshwari P., and Stables J. P. (2000) Synthesis and anticonvulsant activity of 4-bromophenyl substituted aryl semicarbazones. Eur. J. Med. Chem. 35, 879-886.
6. Dutta S., Padhye S., Priyadarsini K. I., and Newton C. (2005) Antioxidant and antiproliferative activity of curcumin semicarbazone. Bioorg. Med. Chem. Lett. 15 (11) 2738-2744.
7. Noriko Chikaraishi Kasuga, Kiyoshi Sekino, Chisa Koumo, Nobuhiro Shimada, Motoki Ishikawa, and Kenji Nomiya. (2001) Synthesis, structural characterization and antimicrobial activities of 4- and 6-coordinate nickel(II) complexes with three thiosemicarbazones and semicarbazone ligands. J. Inorg. Bio. chem. 84, 55-65.
8. Gaonkar S. L., Rai K. M. L., and Prabhuswamy B. (2006) Synthesis and antimicrobial studies of a new series of 2-{4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}-5-substituted-1,3,4-oxadiazoles. Eur. J. Med. Chem. 41, 841-846.
9. Ajay Kumar K., Jayaroopa P., and Vasanth Kumar G. (2012) Comprehensive review on 1,3,4-oxadiazoles and their applications. Int. J. Chem. Tech. Res., 4 (4) 1782-1791.
10. Mohsen M. Aly, Yahia A. Mohamad, Khairy A. M. El-Bayouki, Wahid M. Basyouni, and Samir Y. Abbas. (2010) Synthesis of some new 4(3H)-quinazolinone-2-carboxaldehyde thiosemicarbazones and their metal complexes and a study on their anticonvulsant, analgesic, cytotoxic and antimicrobial activities. Eur. J. Med. Chem. 45, 3365-3373.
11. Antonios Kolocouris, Kostas Dimas, Christophe Pannecouque, Myriam Witvrouw, George B. Foscolos, George Stamatiou, George Fytas, Grigoris Zoidis, Nicolas Kolocouris, Graciela Andrei, Robert Snoeck, and Erik De Clercq. (2002) New 2-(-Adamantylcarbonyl)pyridine and 1-Acetyladamantane Thiosemicarbazones: Cell Growth Inhibitory, Antiviral and Antimicrobial Activity Evaluation. Bio. Med. Chem. Lett. 12, 723-727.
12. Vibha Mishra, Pandeya S. N., Christophe Pannecouque, MyriamWitvrouw, and De Clercq E. (2002) Anti-HIV Activity of Thiosemicarbazone and Semicarbazone Derivatives of (±)-3-Menthone. Arch. Pharm. 5, 183-186.
13. Wei-xiao Hu, Wei Zhou, Chun-nianXia, and Xi Wen. (2006) Synthesis and anticancer activity of thiosemicarbazones. Bioorg. Med. Chem. Lett. 16, 2213-2218.
14. Prakash Karegoudar D., Jagdeesh P., Mithun A., Manjathuru M., Boja P., and Bantwal S.H. (2008) Synthesis, antimicrobial and anti-inflammatory activities of some 1,2,4-triazolo[3,4-b][1,3,4] thiadiazoles and 1,2,4-triazolo[3,4-b][1,3,4] thiadiazines bearing trichlorophenyl moiety. Eur. J. Med. Chem., 43, 808-815.
15. Ajay Kumar K., Renuka N. and Vasanth Kumar G. (2013) Thiadiazoles: Molecules of diverse applications-A review. Int. J. Pharm. Tech. Res., 5 (1) 239-248.
16. Pavithra Gurunanjappa, Renuka Nagamallu, Ajay Kumar Kariyappa. (2015) Synthesis and antimicrobial activity of fused pyrazoles. Int. J. Pharm. Pharm. Sci. 7, 379-381.
17. Renuka N., Pavithra G. and Ajay Kumar K. (2014) Synthesis and their antioxidant activity studies of 1,4-benzothiazepine analogues. Der Pharma Chemica, 6 (1) 482-485.
18. Backman TW., Cao Y., and Girke T. (2011) ChemMine tools: an online service for analyzing and clustering small molecules Nucleic Acids Res. 39, W486-491.
19. Roy K., and Mitra I. (2011)On various metrics used for validation of predictive QSAR models with applications in virtual screening and focused library design. Comb. Chem. High Throughput Screen. 14, 450-474.
20. Renuka Nagamallu, Bharath Srinivasan, Mylarappa B Ningappa, Ajay Kumar Kariyappa. (2016) Synthesis of novel coumarin appended bis(formylpyrazole) derivatives: Studies on their antimicrobial and oxidant activities. Bioorg. Med. Chem. Lett., 26 (2) 690-694.
21. Padmaja A., Rajashekar C., Muralikrishna A., and Padmavathi V. (2011) Synthesis and antioxidant activity of oxazolyl/thiazolylsulfonylmethyl pyrazoles and isoxazoles. Eur. J. Med. Chem. 46, 5034-5038.
22. De Rojas-Walker T.D., Tamir S., Ji H., Wishnok J.S., and Tannenbaum S.R. (1995) Nitrioxide induces oxidative damage in addition to deamination in microphage DNA. Chem. Res. 8, 473-4777.
23. Paul Hochestein, and Ahead S.A. (1988) The nature of oxidants and antioxidant systems in the inhibition of mutation and cancer. Mutat. Res. 202, 363-375.
24. Emmanuel Mukwevho, Zané Ferreira and Ademola Ayeleso. (2014) Potential role of sulfur-containing antioxidant systems in highly oxidative environments. Molecules 19, 19376-19389.