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Growing Science » Current Chemistry Letters » Synthesis and in vitro antioxidant activity of quinolin-5-ylamine derivatives

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Current Chemistry Letters

ISSN 1927-730x (Online) - ISSN 1927-7296 (Print)
Quarterly Publication
Volume 2 Issue 3 pp. 119-124 , 2013

Synthesis and in vitro antioxidant activity of quinolin-5-ylamine derivatives Pages 119-124 Right click to download the paper Download PDF

Authors: L. Mallesha, B.K. Kendagannaswamy, K.N. Mohana

Keywords: Aldehydes, Quinolin-5-ylamine, Antioxidant, DPPH, Ketones

Abstract: Imines of six new quinolin-5-ylamine derivatives 3(a-c) and 5(a-c) were synthesized by the reaction of quinolin-5-ylamine (1) with different aldehydes 2(a-c) and ketones 4(a-c). The chemical structures of the compounds were confirmed by UV-visible, FT-IR and 1H NMR spectral study. New compounds were screened for the antioxidant activity by DPPH (2,2-diphenyl-1-picrylhydrazyl) method. Butylated Hydroxytoluene (BHT) was used as standard. All the compounds showed DPPH radical scavenging activity, where compound 3c was the best radical scavenger.

How to cite this paper
Mallesha, L., Kendagannaswamy, B & Mohana, K. (2013). Synthesis and in vitro antioxidant activity of quinolin-5-ylamine derivatives.Current Chemistry Letters, 2(3), 119-124.

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Journal: Current Chemistry Letters | Year: 2013 | Volume: 2 | Issue: 3 | Views: 2658 | Reviews: 0

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