How to cite this paper
Khalafy, J., Habashi, B., Marjani, A & Moghadam, P. (2012). The synthesis of 2-arylquinoxaline derivatives.Current Chemistry Letters, 1(3), 139-146.
Refrences
1. Zarranz, B., Jaso, A., Aldana, I., and Monge, A. (2004) Synthesis and anticancer activity evaluation of new 2-alkylcarbonyl and 2-benzoyl-3-trifluoromethyl-quinoxaline 1,4-di-N-oxide derivatives, Bioorg. Med. Chem., 12, 3711-3721.
2. Lee, H., Cho, S., Namgoong, K., Jung, J. K., and Yang, S. (2004) Synthesis and in vitro evaluation of 7-dialkylaminomethylbenzo[g]quinoxaline-5,10-diones, Bioorg. Med. Chem. Lett., 14, 1235-1237.
3. Chung, H. J., Jung, O. J., Chae, M. J., Hong, S. Y., Chung, K. H., and Lee, S. K. (2005) Synthesis and biological evaluation of quinoxaline-5,8-diones that inhibit vascular smooth muscle cell proliferation, Bioorg. Med. Chem. Lett., 15, 3380-3384.
4. Amin, K. M., Ismail, M. M. F., Noaman, E., Soliman, D. H., and Ammar, Y. A. (2006) New quinoxaline 1,4-di-N-oxides. Part 1: Hypoxia-selective cytotoxins and anticancer agents derived from quinoxaline 1,4-di-N-oxides, Bioorg. Med. Chem., 14, 6917-6923.
5. Grande, F., Aiello, F., Grazia, O. D., Brizz,i A., Garofalo, A., and Neamati, N. (2007) Synthesis and antitumor activities of a series of novel quinoxalinhydrazides, Bioorg. Med. Chem., 15, 288-294.
6. Diana, P., Martorana, A., Barraja, P., and Montalbaro, A. (2008) Isoindolo[2,1-a]quinoxaline Derivatives, Novel Potent Antitumor Agents with Dual Inhibition of Tubulin Polymerization and Topoisomerase I, J. Med. Chem., 51, 2387-2399.
7. Tandon, V. K., Yadav, D. B., Maurya, H. K., Chaturvedi, A. K., and Shukla, P. K. (2006) Design, synthesis, and biological evaluation of 1,2,3-trisubstituted-1,4-dihydrobenzo[g]quinoxaline-5,10-diones and related compounds as antifungal and antibacterial agents, Bioorg. Med. Chem., 14, 6120-6126.
8. Kotharkar, S. A., and Shinde, D. B. (2006) Synthesis of antimicrobial 2,9,10-trisubstituted-6-oxo-7,12-dihydro-chromeno[3,4-b]quinoxalines, Bioorg. Med. Chem. Lett., 16, 6181-6184.
9. Mashevskaya, I. V., Makhmudov, R. R., Aleksandrova, G. A., Golovnira, O. V., Duvalov, A. V., and Maslivets, A. N. (2001) Synthesis and Study of the Antibacterial and Analgesic Activity of 3-Acyl-1,2,4,5-tetrahydro-[1,2-a]quinoxaline-1,2,4-triones, Pharm. Chem. J., 35, 196-198.
10. Vyas, D. A., Chauhan, N. A., and Parikh, A. R. (2007) Synthesis and anti microbial activity of quinoxaline based thiazolidinones and azetidinones, Indian J. Chem., 46B, 1699-1702.
11. Carta, A., Loriga, M., Paglietti, G., Mattana, A., Fiori, P. L., Mollicotti, P., Sechi, L., and Zanetti, S. Synthesis, anti-mycobacterial, anti-trichomonas and anti-candida in vitro activities of 2-substituted-6,7-difluoro-3-methylquinoxaline 1,4-dioxides, Eur. J. Med. Chem., 39, 195-203.
12. Seitz, L. E., Suling, W. J., and Reynolds, R. C. (2002) Synthesis and Antimycobacterial Activity of Pyrazine and Quinoxaline Derivatives, J. Med. Chem., 45, 5604-5606.
13. Zarranz, B., Jaso, A., Aldana, I., and Monge, A. (2003) Synthesis and antimycobacterial activity of new quinoxaline-2-carboxamide 1,4-di-N-oxide derivatives, Bioorg. Med. Chem., 11, 2149-2156.
14. Jaso, A., Zarranz, B., Aldana, I., and Monge, A.(2005) Synthesis of New Quinoxaline-2-carboxylate 1,4-Dioxide Derivatives as Anti-Mycobacterium tuberculosis Agents, J. Med. Chem., 48, 2019-2025.
15. Burguete, A., Pontiki, E., Litina, D. H., Villar, R., Vicente, E., Solano, B., Ancizu, S., Aldana, I., and Monge, A. (2007) Synthesis and anti-inflammatory/antioxidant activities of some new ring substituted 3-phenyl-1-(1,4-di-N-oxide quinoxalin-2-yl)-2-propen-1-one derivatives and of their 4,5-dihydro-(1H)-pyrazole analogues, Bioorg. Med. Chem. Lett., 17, 6439-6443.
16. Wagle, S., Adhikari, A. V., and Kumari, N. S. (2008) Synthesis of Some New 2-(3-Methyl-7-substituted-2-oxoquinoxalinyl)-5-(aryl)-1,3,4-oxadiazoles as Potential Nonsteroidal Antiinflammatory and Analgesic Agents, Indian J. Chem., 47B, 439-448.
17. Jasouri, S., Khalafy, J., Badali, M., and Prager, R. H. (2011) Synthesis of 9H-indeno [1,2-b] pyrazine and 11H-indeno[1,2-b]quinoxaline derivatives in one-step reaction from 2-bromo-4-chloro-1-indanone, S. Afri. J. Chem., 64, 105-107.
18. Poursattar Marjani, A., Khalafy, J., and Prager, R. H. (2012) A novel synthesis of imidazo[1,2-a]quinoxalines, Khim. Geterotsikl. Soedin., 48, in press.
19. Riley, H. A., and GraY, A. R. (1943) Organic Syntheses, Collect. Vol. II, p. 509 (Wiley & Sons: New York, NY).
2. Lee, H., Cho, S., Namgoong, K., Jung, J. K., and Yang, S. (2004) Synthesis and in vitro evaluation of 7-dialkylaminomethylbenzo[g]quinoxaline-5,10-diones, Bioorg. Med. Chem. Lett., 14, 1235-1237.
3. Chung, H. J., Jung, O. J., Chae, M. J., Hong, S. Y., Chung, K. H., and Lee, S. K. (2005) Synthesis and biological evaluation of quinoxaline-5,8-diones that inhibit vascular smooth muscle cell proliferation, Bioorg. Med. Chem. Lett., 15, 3380-3384.
4. Amin, K. M., Ismail, M. M. F., Noaman, E., Soliman, D. H., and Ammar, Y. A. (2006) New quinoxaline 1,4-di-N-oxides. Part 1: Hypoxia-selective cytotoxins and anticancer agents derived from quinoxaline 1,4-di-N-oxides, Bioorg. Med. Chem., 14, 6917-6923.
5. Grande, F., Aiello, F., Grazia, O. D., Brizz,i A., Garofalo, A., and Neamati, N. (2007) Synthesis and antitumor activities of a series of novel quinoxalinhydrazides, Bioorg. Med. Chem., 15, 288-294.
6. Diana, P., Martorana, A., Barraja, P., and Montalbaro, A. (2008) Isoindolo[2,1-a]quinoxaline Derivatives, Novel Potent Antitumor Agents with Dual Inhibition of Tubulin Polymerization and Topoisomerase I, J. Med. Chem., 51, 2387-2399.
7. Tandon, V. K., Yadav, D. B., Maurya, H. K., Chaturvedi, A. K., and Shukla, P. K. (2006) Design, synthesis, and biological evaluation of 1,2,3-trisubstituted-1,4-dihydrobenzo[g]quinoxaline-5,10-diones and related compounds as antifungal and antibacterial agents, Bioorg. Med. Chem., 14, 6120-6126.
8. Kotharkar, S. A., and Shinde, D. B. (2006) Synthesis of antimicrobial 2,9,10-trisubstituted-6-oxo-7,12-dihydro-chromeno[3,4-b]quinoxalines, Bioorg. Med. Chem. Lett., 16, 6181-6184.
9. Mashevskaya, I. V., Makhmudov, R. R., Aleksandrova, G. A., Golovnira, O. V., Duvalov, A. V., and Maslivets, A. N. (2001) Synthesis and Study of the Antibacterial and Analgesic Activity of 3-Acyl-1,2,4,5-tetrahydro-[1,2-a]quinoxaline-1,2,4-triones, Pharm. Chem. J., 35, 196-198.
10. Vyas, D. A., Chauhan, N. A., and Parikh, A. R. (2007) Synthesis and anti microbial activity of quinoxaline based thiazolidinones and azetidinones, Indian J. Chem., 46B, 1699-1702.
11. Carta, A., Loriga, M., Paglietti, G., Mattana, A., Fiori, P. L., Mollicotti, P., Sechi, L., and Zanetti, S. Synthesis, anti-mycobacterial, anti-trichomonas and anti-candida in vitro activities of 2-substituted-6,7-difluoro-3-methylquinoxaline 1,4-dioxides, Eur. J. Med. Chem., 39, 195-203.
12. Seitz, L. E., Suling, W. J., and Reynolds, R. C. (2002) Synthesis and Antimycobacterial Activity of Pyrazine and Quinoxaline Derivatives, J. Med. Chem., 45, 5604-5606.
13. Zarranz, B., Jaso, A., Aldana, I., and Monge, A. (2003) Synthesis and antimycobacterial activity of new quinoxaline-2-carboxamide 1,4-di-N-oxide derivatives, Bioorg. Med. Chem., 11, 2149-2156.
14. Jaso, A., Zarranz, B., Aldana, I., and Monge, A.(2005) Synthesis of New Quinoxaline-2-carboxylate 1,4-Dioxide Derivatives as Anti-Mycobacterium tuberculosis Agents, J. Med. Chem., 48, 2019-2025.
15. Burguete, A., Pontiki, E., Litina, D. H., Villar, R., Vicente, E., Solano, B., Ancizu, S., Aldana, I., and Monge, A. (2007) Synthesis and anti-inflammatory/antioxidant activities of some new ring substituted 3-phenyl-1-(1,4-di-N-oxide quinoxalin-2-yl)-2-propen-1-one derivatives and of their 4,5-dihydro-(1H)-pyrazole analogues, Bioorg. Med. Chem. Lett., 17, 6439-6443.
16. Wagle, S., Adhikari, A. V., and Kumari, N. S. (2008) Synthesis of Some New 2-(3-Methyl-7-substituted-2-oxoquinoxalinyl)-5-(aryl)-1,3,4-oxadiazoles as Potential Nonsteroidal Antiinflammatory and Analgesic Agents, Indian J. Chem., 47B, 439-448.
17. Jasouri, S., Khalafy, J., Badali, M., and Prager, R. H. (2011) Synthesis of 9H-indeno [1,2-b] pyrazine and 11H-indeno[1,2-b]quinoxaline derivatives in one-step reaction from 2-bromo-4-chloro-1-indanone, S. Afri. J. Chem., 64, 105-107.
18. Poursattar Marjani, A., Khalafy, J., and Prager, R. H. (2012) A novel synthesis of imidazo[1,2-a]quinoxalines, Khim. Geterotsikl. Soedin., 48, in press.
19. Riley, H. A., and GraY, A. R. (1943) Organic Syntheses, Collect. Vol. II, p. 509 (Wiley & Sons: New York, NY).