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Growing Science » Current Chemistry Letters » Batch and merging-zone flow injection methods for determination of tetracycline hydrochloride

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Current Chemistry Letters
ISSN 1927-730x (Online) - ISSN 1927-7296 (Print)
Quarterly Publication
Volume 12 Issue 4 pp. 677-684, 2023

Batch and merging-zone flow injection methods for determination of tetracycline hydrochloride Pages 677-684 PDF Download PDF

Authors: Esraa Rasool Radhi, Khdeeja Jabbar Ali, Fatima Hydar Abdul Hussein

📋 Author Affiliations:
E.R. Radhi ORCID 1, K.J. Ali ORCID 2, F.H.A. Hussein ORCID 3
1 Ministry of Education, Kufa, Iraq
2 Chemistry Department, Education for Girls Faculty, Kufa University, Kufa, Iraq
3 Faculty of Pharmacy, Kufa University, Kufa, Iraq
doi 10.5267/j.ccl.2023.6.001
4 Source: Scopus
Crossref 3 Source: CrossRef

🔑 Keywords: Flow Injection System, Batch Methods, Tetracycline Hydrochloride, Determination, Potassium Permanganate

Abstract: The objective of the present work is to develop batch and merging-zone flow injection methods for sensitive and accurate spectrophotometric determination of tetracycline hydrochloride. The methods depend on the oxidation of the studied drug with potassium permanganate in an alkaline medium, and the absorbance of the green oxidation product was measured at 610 nm. The calibration graphs in both procedures were linear in the concentration ranges of 0.5 – 25 and 1 – 25 μg mL−1 using the spectrophotometric and merging-zone flow injection methods, respectively. Specific and molar absorption coefficients, limits of detection and quantification, and Sandell’s sensitivity were calculated. The suggested procedures were further applied to the quantitative determination of tetracycline in pharmaceutical formulations.

How to cite this paper
APA: Radhi, E., Ali, K & Hussein, F. (2023). Batch and merging-zone flow injection methods for determination of tetracycline hydrochloride. Current Chemistry Letters, 12(4), 677-684.
Chicago/Turabian: Radhi, E., Ali, K & Hussein, F. 2023. "Batch and merging-zone flow injection methods for determination of tetracycline hydrochloride." Current Chemistry Letters 12, no. 4 (2023): 677-684.
AMA: Radhi, E., Ali, K & Hussein, F. Batch and merging-zone flow injection methods for determination of tetracycline hydrochloride. Current Chemistry Letters. 2023;12(4):677-684.

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📚 Journal: Current Chemistry Letters | 📅 Year: 2023 | 📖 Volume: 12 | 📄 Issue: 4 | 👁️ Views: 1262 | 📊 Crossref: 3

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