Processing, Please wait...

  • Publisher Home
  • Home
  • 🔙 Back
  • 📚 Journals
    • ⚙️ IJIEC - Industrial Engineering Computations
    • 🌐 IJDNS - Data and Network Science
    • 🧪 CCL - Current Chemistry Letters
    • 💹 AC - Accounting
    • 🎯 DSL - Decision Science Letters
    • 🚛 USCM - Uncertain Supply Chain Management
    • 🏗️ JPM - Journal of Project Management
    • 🏥 HE - Healthcare Engineering
    • 📈 SCI - Scientometrica
    • 🔩 ESM - Engineering Solid Mechanics
    • 🌿 JFS - Journal of Future Sustainability
    • 💼 MSL - Management Science Letters
  • 📝 Submit Article
  • 📊 Statistics
  • 📋 About
    • 📄 About Us
    • 📰 Blog
    • 📢 News
    • 📧 Contact
  • 📺 Tutorial
  • Search:
  • Advanced Search

Growing Science » Current Chemistry Letters » Eco-friendly ultraviolet spectrophotometric methods for the determination of clotrimazole and tinidazole in bulk and ointment dosage form

⭐ Highly Cited Articles

  • Jaya Algorithm
  • Rao Algorithm
  • TLBO Algorithm
  • ChatGPT and Blended Learning

Journals

  • IJIEC (840)
  • IJDS (1032)
  • DSL (759)
  • ESM (434)
  • CCL (563)
  • JPM (350)
  • AC (572)
  • JFS (106)
  • MSL (2658)
  • USCM (1104)
  • HE (54)
  • SCI (53)

CCL Volumes

    • ▼ Volume 15 (68)
      • Issue 1 (13)
      • Issue 2 (20)
      • Issue 3 (16)
      • Issue 4 (19)
    • ▼ Volume 14 (68)
      • Issue 1 (20)
      • Issue 2 (13)
      • Issue 3 (22)
      • Issue 4 (13)
    • ▼ Volume 13 (68)
      • Issue 1 (23)
      • Issue 2 (17)
      • Issue 3 (16)
      • Issue 4 (12)
    • ▼ Volume 12 (78)
      • Issue 1 (21)
      • Issue 2 (22)
      • Issue 3 (20)
      • Issue 4 (15)
    • ▼ Volume 11 (43)
      • Issue 1 (14)
      • Issue 2 (11)
      • Issue 3 (10)
      • Issue 4 (8)
    • ▼ Volume 10 (43)
      • Issue 1 (5)
      • Issue 2 (7)
      • Issue 3 (17)
      • Issue 4 (14)
    • ▼ Volume 9 (20)
      • Issue 1 (5)
      • Issue 2 (5)
      • Issue 3 (5)
      • Issue 4 (5)
    • ▼ Volume 8 (20)
      • Issue 1 (5)
      • Issue 2 (5)
      • Issue 3 (5)
      • Issue 4 (5)
    • ▼ Volume 7 (15)
      • Issue 1 (4)
      • Issue 2 (4)
      • Issue 3 (4)
      • Issue 4 (3)
    • ▼ Volume 6 (20)
      • Issue 1 (5)
      • Issue 2 (5)
      • Issue 3 (5)
      • Issue 4 (5)
    • ▼ Volume 5 (20)
      • Issue 1 (5)
      • Issue 2 (5)
      • Issue 3 (5)
      • Issue 4 (5)
    • ▼ Volume 4 (21)
      • Issue 1 (5)
      • Issue 2 (5)
      • Issue 3 (6)
      • Issue 4 (5)
    • ▼ Volume 3 (30)
      • Issue 1 (7)
      • Issue 2 (10)
      • Issue 3 (8)
      • Issue 4 (5)
    • ▼ Volume 2 (26)
      • Issue 1 (7)
      • Issue 2 (6)
      • Issue 3 (6)
      • Issue 4 (7)
    • ▼ Volume 1 (23)
      • Issue 1 (7)
      • Issue 2 (5)
      • Issue 3 (6)
      • Issue 4 (5)

🔑 Keywords

Jordan(175)
Supply chain management(172)
Vietnam(154)
Customer satisfaction(124)
Performance(117)
Supply chain(115)
Artificial intelligence(108)
Service quality(101)
Competitive advantage(100)
SMEs(95)
Sustainability(94)
Tehran Stock Exchange(94)
optimization(88)
Financial performance(86)
TOPSIS(85)
Trust(85)
Genetic Algorithm(81)
Organizational performance(81)
Job satisfaction(81)
Social media(80)


» Show all keywords

✍️ Authors

Naser Azad(82)
Zeplin Jiwa Husada Tarigan(70)
Mohammad Reza Iravani(65)
Endri Endri(45)
Hotlan Siagian(43)
Muhammad Alshurideh(42)
Dmaithan Almajali(39)
Jumadil Saputra(37)
Muhammad Turki Alshurideh(35)
Ahmad Makui(33)
Sautma Ronni Basana(33)
Barween Al Kurdi(32)
Basrowi Basrowi(31)
Mohammad Khodaei Valahzaghard(30)
Haitham M. Alzoubi(30)
Ni Nyoman Kerti Yasa(30)
Hassan Ghodrati(30)
Shankar Chakraborty(29)
Sulieman Ibraheem Shelash Al-Hawary(28)
Mahmoud Allahham(28)


» Show all authors

🌍 Countries

1. Algeria (52)
2. Angola (2)
3. Argentina (22)
4. Armenia (2)
5. Australia (52)
6. Austria (2)
7. Bahrain (26)
8. Bangladesh (58)
9. Belarus (4)
10. Belgium (3)
11. Benin (2)
12. Benin Republic (1)
13. Bhutan (1)
14. Bosnia and Herzegovina (1)
15. Botswana (9)
16. Brazil (40)
17. Brunei (1)
18. Bulgaria (1)
19. Burkina Faso (1)
20. Cameroon (1)
Total: 121 countries

Show all countries
Current Chemistry Letters
ISSN 1927-730x (Online) - ISSN 1927-7296 (Print)
Quarterly Publication
Volume 11 Issue 1 pp. 11-22, 2022

Eco-friendly ultraviolet spectrophotometric methods for the determination of clotrimazole and tinidazole in bulk and ointment dosage form Pages 11-22 PDF Download PDF

Authors: Kanaka Parvathi Kannaiah, Abimanyu Sugumaran

📋 Author Affiliations:
K.P. Kannaiah, A. Sugumaran ORCID
¹ SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, 603203, India
doi 10.5267/j.ccl.2021.11.001
11 Source: Scopus
Crossref 11 Source: CrossRef

🔑 Keywords: Clotrimazole, Tinidazole, Ethanol, Eco-friendly method, UV spectrophotometry

Abstract: Analyzing a drug over its overlapped spectra utilizes sophisticated instruments and more toxic solvents, which has a deleterious effect on environmental safety. There is an alarming need to develop a simple, novel, and cost-effective method for determining combined substances that are non-toxic to the environment. So, the study aimed to develop four simple, fast and eco-friendly spectrophotometric techniques for quantifying clotrimazole and tinidazole in bulk and ointment dosage form. Stock solutions produced at concentrations of 7 to 13 and 17.5 to 32.5 µg/mL of clotrimazole and tinidazole in 10% v/v ethanol and scanned in the UV-visible range 200-450 nm, and used for all methods. The methods were validated according to the International Council for Harmonization guidelines and found to be within limits. Additionally, the outliers were tested by using the Grubbers test and found within limits. Finally, green evaluation studies show that the method is more environmentally friendly, as confirmed by four assessment tools.

How to cite this paper
APA: Kannaiah, K & Sugumaran, A. (2022). Eco-friendly ultraviolet spectrophotometric methods for the determination of clotrimazole and tinidazole in bulk and ointment dosage form. Current Chemistry Letters, 11(1), 11-22.
Chicago/Turabian: Kannaiah, K & Sugumaran, A. 2022. "Eco-friendly ultraviolet spectrophotometric methods for the determination of clotrimazole and tinidazole in bulk and ointment dosage form." Current Chemistry Letters 11, no. 1 (2022): 11-22.
AMA: Kannaiah, K & Sugumaran, A. Eco-friendly ultraviolet spectrophotometric methods for the determination of clotrimazole and tinidazole in bulk and ointment dosage form. Current Chemistry Letters. 2022;11(1):11-22.

References

1. Moriarty B. Hay R. and Morris-Jones R. (2012) The diagnosis and management of tinea. BMJ., 345.
2. Speelman P. (1985) Single-dose tinidazole for the treatment of giardiasis. Antimicrob. Agents Chemother., 27 (2) 227–9.
3. Armstrong N. R. and Wilson J. D. (2010) Tinidazole in the treatment of bacterial vaginosis. Int. J. Womens. Health., 1 59–65.
4. Packard R. S. (1982) Tinidazole: a review of clinical experience in anaerobic infections. J. Antimicrob. Chemother., 10 (suppl_A) 65–78.
5. L,SINGH; S N. (2011) Method for Determination of Tinidazole using Direct UV-Visible Spectrophotometry and Differential Spectrophotometry in Pure and Tablet Dosage Forms. East Cent. African J. Pharm. Sci., 14 75–80.
6. Siddartha B. Sudheer Babu I. Parthiban C. and Prathyusha V. (2014) Method development and method validation of tinidazole in bulk and pharmaceutical dosage form by UV- spectrophotometric method. Res. J. Pharm. Technol., 7 (4) 467–9.
7. Mahmood S. Ahmad Z. Aslam M. Naeem F. Hussain A. and Kumar N. (2015) Method Development and Validation for the Estimation and Evaluation of Clotrimazole (an-Antifungal Drug) in Tablet Preparation by UV-VIS Spectroscopy. Int. J. Pharm. Sci. Rev. Res., 32 55–8.
8. Salo J. P. K. and Salomies H. (2003) Two stability-indicating UV spectrophotometric methods for the analysis of hydrolyzed tinidazole. J. Pharm. Biomed. Anal., 31 (3) 523–36.
9. Mayank P. Khemchand D. and Khatri N. C. (2012) Application of UV spectrophotometric methods for estimation of ciprofloxacin and tinidazole in combined tablet dosage form. Der Pharma Chem., 4 (SUPPL.3) 1041–6.
10. Mahmood S. Ahmad Z. Aslam M. Naeem F. Hussain A. and Kumar N. (2015) Method development and validation for the estimation and evaluation of clotrimazole (an-antifungal drug) in tablet preparation by UV-VIS spectroscopy. Int. J. Pharm. Sci. Rev. Res., 32 (2) 55–8.
11. Ismail N. B. S. and Narayana B. (2017) Spectrophotometric and spectroscopic studies on charge transfer complexes of the antifungal drug clotrimazole. J. Taibah Univ. Sci., 11 (5) 710–7.
12. velmuruganaƒ D. vairavel S. chandran R. . S. and nayak S. K. (2019) A Study Of Method Development, Validation and Forced Degradation Studies of Clotrimazole by Using UV Spectrophotometry. Am. J. PharmTech Res., 9 (2) 45–53.
13. Naguib I. A. Abdelaleem E. A. Hassan E. S. Ali N. W. and Gamal M. (2020) Partial least squares and linear support vector regression chemometric models for analysis of Norfloxacin and Tinidazole with Tinidazole impurity. Spectrochim. Acta - Part A Mol. Biomol. Spectrosc., 239 118513.
14. Priyanka C. P. Dr. Shailesh V. L. and Narkhede D. S. B. (2018) Analytical method development & validation for clindamycin, clotrimazole & tinidazole in pharmaceutical dosage form. Biomed. Eur. Pharm. Sci., 5 (5) 635–54.
15. Hemdan Abou-Taleb N. Mahmoud El-Enany N. Tawfik El-Sherbiny D. and Ibrahim El-Subbagh H. (2020) Digitally enhanced thin layer chromatography for simultaneous determination of norfloxacin and tinidazole with the aid of Taguchi orthogonal array and desirability function approach: Greenness assessment by analytical Eco-Scale. J. Sep. Sci., 43 (6) 1195–202.
16. Mali A. D. (2015) Estimation of domperidone in bulk and formulation by first order derivative area under curve UV-Spectrophotometry methods. Int. J. Pharm. Technol., 7 (1) 8040–8.
17. Chalikwar S. S. Shirkhedkar A. A. Bagul M. A. Jain P. S. and Surana S. J. (2012) Development and validation of zero and first-order derivative area under curve spectrophotometric methods for the determination of entacapone in bulk material and in tablets. Pharm. Methods., 3 (1) 14–7.
18. Korany M. A. Mahgoub H. Haggag R. S. Ragab M. A. A. and Elmallah O. A. (2017) Green chemistry: Analytical and chromatography. J. Liq. Chromatogr. Relat. Technol., 40 (16) 839–52.
19. Płotka-Wasylka J. (2018) A new tool for the evaluation of the analytical procedure: Green Analytical Procedure Index. Talanta., 181 204–9.
20. Tobiszewski M. (2016) Metrics for green analytical chemistry. Anal. Methods., 8 (15) 2993–9.
21. Kannaiah K. and Sugumaran A. (2021) ECO-FRIENDLY MULTIVARIANT GREEN ANALYTICAL TECHNIQUE FOR THE ESTIMATION OF KETOCONAZOLE BY UV SPECTROSCOPY IN BULK AND CREAM FORMULATION. Quim. Nova.,.
22. Pena-Pereira F. Wojnowski W. and Tobiszewski M. (2020) AGREE—Analytical GREEnness Metric Approach and Software. Anal. Chem., 92 (14) 10076–82.
23. Li Z. Smith K. H. and Stevens G. W. (2016) The use of environmentally sustainable bio-derived solvents in solvent extraction applications - A review. Chinese J. Chem. Eng., 24 (2) 215–20.
24. Henderson R. K. Jiménez-González C. Constable D. J. C. et al. (2011) Expanding GSK{’}s solvent selection guide – embedding sustainability into solvent selection starting at medicinal chemistry. Green Chem., 13 (4) 854–62.
25. US EPA. (2015) O. US EPA, defining hazardous waste: listed, characteristic and mixed radiological wastes, US EPA.
26. Kanaka Parvathi K. Sugumaran A. Hemanth Kumar C. and Seetharaman R. (2021) Environmental Impact of Greenness Assessment Tools in Liquid Chromatography – A Review. Microchem. J., 106685.
  • 0
  • 1
  • 2
  • 3
  • 4
  • 5

📚 Journal: Current Chemistry Letters | 📅 Year: 2022 | 📖 Volume: 11 | 📄 Issue: 1 | 👁️ Views: 1759 | 📊 Crossref: 11

Related Articles:
  • Isocratic RP-UHPLC method development and validation of stability-indicating for simultaneous determination of teneligliptin and metformin in fixed-dose combination
  • Novel membrane sensor for determination of lamotrigine in pharmaceuticals and urine
  • Spectrophotometric assay of pioglitazone hydrochloride using permanganate in acidic and basic media
  • Potentiometric determination of piroxicam and oxfendazole in pharmaceuticals
  • Spectrophotometric determination of Naproxen as ion-pair with bromophenol blue in bulk, pharmaceutical preparation and human serum samples

📝 Ready to share your research?

Current Chemistry Letters is accepting new submissions for upcoming issues. Join our community of authors and publish your work with us.

✓ Open access
✓ Rigorous peer review
✓ Fast publication
📤 Submit Your Manuscript →

📖 Author Guidelines

® 2010-2026 GrowingScience.Com