Transition to the digital economy determines the readiness of the national economy complex for the emergence of new industries, forms of economic cooperation, and general development of the regional economy on the whole, both for a separate region and for the entire country. Authors determine the possibility of application of digital transformations in regional devel-opment. This is due to the fact that the Republic of Kazakhstan is a country with widely dif-ferentiated regional development. This means that regional development should be proceed not only from the application of digital technology directly within the regional economy, but also from the introduction of digital technology in certain sectors of the industrial complex. The novelty of the study lies in the determination of the possibility of implementing digital technology as an integral part of the economy and the possibility of clustering individual industries on the basis of digital platforms and communication technology. The authors provide mathematical justification of the integration model for digital complexes within various economy sectors of individual regions. Authors propose using the developed mechanism for structuring the current situation of regional economic development. The practical significance of the study is determined upon designing regional developmen