The aim of this research is to investigate the effects of different factors on Vietnamese consumers’ online shopping intention based on Technology Acceptance Model (TAM) and Theory of Planned Behavior (TPB). A questionnaire was designed and sent directly to the respondents through the Internet. After 5 months period of collecting the necessary data, 423 valid replies were collected and analyzed. The data were analyzed in accordance with exploratory factor analysis (EFA) and multiple regression techniques. The results show that perceived usefulness, perceived ease of use, attitude, subjective norm and trust had positive effects on consumers’ online shopping intention.