This article aims to identify the drivers of the life satisfaction and happiness according to basic demands explored in motivational theories and the inclusion of the need for association participation. Structured questionnaire was directly delivered to 454 poor families living in nine districts of Can Tho. The data was processed by using SmartPLS with partial least squares (PLS) technique. The study found that existence needs, growth needs and needs of association participation can mostly explain the model which remarkably contribute to the literature of life satisfaction and happiness. In addition, the needs for association participation and life satisfaction positively affect people’s life happiness. In order to improve the living standards of local people, the government should clearly understand what residents really target to in life and fundamental demands of survive and self-development should be carefully considered and supported by the local authority and private organizations.