Foam made panels as efficient building elements are becoming a major role player in modular construction with a variety of applications worldwide. However, construction accuracy, technology, and method can have serious effects on the panels’ behavior. In this study, using a unique pneumatic pressure testing rig, bending tests are conducted on the two types of rigid polyurethane panels. The panels are categorized based on the existence of construction cold joints (seams) as S (Seamless) type and TS (Transverse Seams) type. The S type panels are tested under monotonic uniform loading with a maximum nominal pressure of about 1 atm as the witness specimens. The TS panels are tested under both monotonic and cyclic uniform loading, and the deflections-pressure behavior obtained. The results show that S panels could resist up to 0.77 atm under monotonic uniform loading, while the minimum tensile strength of the foam is 13 MPa. In addition, panels with transverse seams collapsed under monotonic and cyclic loads at an average of 0.46 atm and 0.33 atm respectively but at the same position, located on the seamed section, which represent the same failure mode. Based on the results, the seamed section exhibited a maximum tensile strength of about 33.1% of an intact section under monotonic loading; and 27.9% lower results under cyclic loading.