With the inception of high-speed internet data services and ever-growing technical advancement in manufacturing technology, the integration of production systems and the internet of things to produce different types of jobs via cloud computing has become possible. The internet-enabled advanced automatic production systems can be referred to as the cyber-physical production systems (CPPS). The use of CPPS via cloud computing and the internet of things (IoT) can offer high productivity and high flexibility for the production of jobs in a dynamic production environment with varying specifications. The aim of this paper is to present a generalized synergic framework between different production facilities locating at different geographical locations to realize an energy-saving and efficient cyber-physical production system for the production of different types of jobs in the context of the industry 4.0 and beyond. In addition to the above, the study also identifies a need to address large scale multi-objective optimization issues to make the best decisions for different combinatorial production scenarios by using CPPS that are functioning in smart production facilities at different geographical locations.