Performance of mines can be affected by different factors such as safety and economic factors. This study aims to analyze the influence of safety and economic factors on mines’ performance. To this purpose, a framework is proposed based on a Data Envelopment Analysis (DEA), Ro-bust Data Envelopment Analysis (RDEA) and common weight Robust Data Envelopment Anal-ysis (CWRDEA) to determine the factors affecting on performance of mines. In this study, for the first time, integrated economic and safety factors are considered for evaluation of mines per-formance. To analyze safety and economic factors, this research gathers real data from a mine with 56 sites in south of Iran. Based on different DEA models, different sites become the best site among other sites, but RDEA is much closer to real situation than basic DEA and CWRDEA is the most efficient approach in real situation.