This paper presents an empirical investigation to study the effects of teaching contrastive skills of Islam originated from versus of holly book of Quran and cognitive-behavioral for coping on anxiety among some high school students in city of Tehran, Iran. The study uses a standard method developed by Cattell and Scheier (1963) [Cattell, R. B., & Scheier, I. H. (1963). Handbook for the IPAT Anxiety Scale Questionnaire: Self Analysis Form. Institute for Personality & Ability Testing.] to measure the anxiety. The results have indicated that both methods, contrastive skills and cognitive-behavioral, not only could reduce anxiety in short term but also it could reduce the anxiety over the long term period.