The study aims to examine the impact of supply chain linkages on the performance of businesses. Quantitative research is used by implementing the analysis of the SEM linear structure model. A survey is conducted consisting of 598 samples - experienced managers who had the knowledge of the management of supply chain activities in enterprises in Vietnam. Research results show that supply chain linkages, although not having a direct impact, has an indirect impact on the business performance of enterprises through the intermediary factors of trust and business strategy and the opportunistic behaviors of the participating members. Also, research has demonstrated that opportunistic behaviors have negative effects on trust among members of the supply chain.