The study aimed at determining the extent to which Jordanian medical devices adopted the supply chain practices and to investigate the impact of those practices on organizational performance of the Jordanian medical devices’ firms. A cross-sectional approach was used to meet the purpose. A robust questionnaire was designed and used to collect primary data from the study sample. 200 questionnaires were completed and returned by the participants. SPSS version 21 and SEM were employed, with the use of (AMOS:21) to analyze and explain the collected data and to validate the research framework. The results demonstrated that medical devices firms in Jordan have adopted the supply chain practices and revealed a significant impact of those practices on the performance of the medical devices in Jordanian context.