The objective of the article is to evaluate the role of laws and regulations on food safety in the implementation of food safety laws in Vietnam. Food safety regulations through business orientation, supply chain dynamic capabilities, and supply chain integration aim to ensure food safety and improve firm performance in Vietnam. Research data analysis is based on 389 food firms and the data are analyzed through Smart PLS 3.3.0 software. The results show the important role of food safety law in the implementation of food safety assurance of food enterprises. At the same time, supply chain dynamics and supply chain integration are also factors that have a statistically significant positive impact on the food safety performance of food enterprises in Vietnam.