The success of building construction projects in developing countries heavily relies on the specialized skills of artisans who are responsible for executing physical construction activities. However, the performance of these artisans depends on various influencing factors (IFs) that significantly affect their productivity and workmanship. This study aims to assess the impact of disregarding IFs on the performance of artisans in building construction projects in Tanzania. Using the individual performance theory, the study identifies the core IFs that influence artisans' performance and develops a structural equation modelling (SEM) to understand the inter-relationship between these IFs. The study collects data from 289 building construction projects through a non-probability technique and analyses it using SPSS-25 and AMOS-20. The study finds that the enforcement of IFs at construction sites by stakeholders in the construction industry is weak, which undermines the performance of artisans. Therefore, the study recommends that employers and supervisors should consider IFs during the construction process to achieve better results in terms of time, cost, and quality. The findings of this study can guide employers and supervisors in the construction industry to enhance the overall performance of building construction projects by improving the performance of artisans through ensuring that IFs are taken into consideration during the recruitment and construction process.