This paper reports the findings of a study examining the relationship between transformational leadership, work engagement and workplace spirituality of academic employees in four PHEIs in Malaysia. The perceptions of academic employees regarding the transformational leadership style, work engagement and workplace spirituality were assessed in an empirical study on a sample of 369 full-time academic employees working in higher education institutions in Malaysia. The study found a satisfactorily good level of influence between transformational leadership and workplace spirituality and work engagement. The paper also provides insights into enhancing employees work engagement via transformational leaders through their abilities to create work-place spirituality. The findings also provide evidence that transformational leaders play a crucial role in shaping workplace spirituality and employee’s level of work engagement in an emerging country work setting.