In connection with the global financial and economic crisis, the leading countries have made adjustments to the economic strategies and policies to stabilize the post-crisis economy. The goal of transnationalization is, on the one hand, to reduce quickly the technological gap between domestic producers and their Western competitors, and on the other hand, to win more dynamic demand at lower costs. Ownership structure and market positioning have become two factors that determine the strategic motivation of Transnational corporations (TNCs) and the ways of their expansion. The aim of the study is to analytically generalize the globalization trends of TNCs in the field of production, taking into account industry definitions and point determination of factors influencing the effectiveness of its adaptation in industry. The profiles of adaptation of transnationalization in the sphere of production of Germany, France and the Netherlands were singled out in separate analytical sets, which allowed to reveal heterogeneity of economic practices and branch changes in the sphere of production and to determine the degree of influence of array of variables (factors): Production value and Gross operating surplus profitability of multinational companies, in the sectoral context (domestic production, ISIC Rev 4, 21 industry), as a “basket” of reserve instruments to increase the profitability of production in TNCs.