Small and Medium Enterprises (SME’s), and Entrepreneurial businesses (EB) play an important role in tourism since tourism has increasingly become the largest economic sector. Entrepreneurships known as a mean of economic development and policymakers are looking for creating a competitive and dynamic entrepreneurial economy. The aim of this study is to present a model for entrepreneurship tourism policy by using entrepreneurship development framework, which interacts with economic development. To this purpose, entrepreneurship policy dimensions are weighted and prioritized by tourism entrepreneurs, tourism policymakers and experts using decision-making trial and evaluation laboratory (DEMATEL) technique and Analytical Network Process (ANP) technique. First, DEMATEL technique is used to identify complex relationships, and to form a network relationship map. Then, ANP technique is used to calculate the influential weights of policy criteria. Results show that policymakers for entrepreneurship development in tourism need to consider basic requirements factors. In addition, they should improve efficiency enhancer criteria as well as innovation driver criteria. Also, the relationship among dimensions and their influences on each other are illustrated. Using the capabilities of this method, we can determine the casual relationships between dimensions and criteria and identify priorities for policy.