There are few studies addressing the mediating effect of readiness in supply chains in developing countries. We use the theory of dynamic capabilities to investigate the impact of integration (INT) on readiness (REA) and on innovative product performance (IPP) and to examine the mediating effect of REA on INT and IPP. We conducted a survey with a sample of 213 supply chain (SC) managers of machinery and equipment for transport and lifting heavy loads in Brazil. To this end, we used structural equation modeling to test the hypotheses and PROCESS macro to confirm the indirect effect. The empirical results indicate a significant effect between INT and REA and REA and IPP. However, the indirect impact of REA was compromised. The literature review demonstrates that the microfoundations of dynamic capabilities (Sensing, Seizing and Reconfiguration) strengthen supply chain links, particularly between INT, REA and IPP. This article helps managers understand the functioning of SC routines and operations. To this end, they should develop strategies that strengthen SC ties with INT, REA and IPP to face future crises. This paper advances the findings on integration, readiness, and innovative product performance in an SC. The findings provide insightful implications for managers to improve their strategies. In doing so, we theorize how the microfoundations of dynamic capabilities support the efficiency of supply chain operations.