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Growing Science » Authors » Razieh Mohammadnejad Aghdam

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1.

Synthesis of new heterocyclic compounds using 2-(4,7-dichloro-3,3-dimethyl-indolin-2-ylidene)malonaldehyde Pages 13-20 Right click to download the paper Download PDF

Authors: Razieh Mohammadnejad Aghdam, Mehdi M. Baradarani, Arash Afghan

DOI: 10.5267/j.ccl.2012.10.001

Keywords: Malondialdehyde, Pyrazole- Pyrimidone, Thiopyrimidone, Vilsmeier reagent

Abstract:
1-(2,5-Dichlorophenyl)hydrazine was converted via Fischer synthesis with isopropylmethylketone into 4,7-dichloro-2,3,3-trimethyl-3H-indole. Exposure of the indolenine to the vilsmeier reagent produced amino methylene malondialdehyde which reacted with hydrazine, arylhydrazine, urea, cyanoacetamide and thiourea to give pyrazols, pyrimidones and thiopyrimidone, respectively.
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Journal: CCL | Year: 2013 | Volume: 2 | Issue: 1 | Views: 2794 | Reviews: 0

 

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