The SMEs is currently experiencing many challenges, especially performance improvements. To improve performance, companies are required to increase the effective organizational learning so that it is emphasized on improving human resource development in addition to being able to overcome market uncertainty. This study examined empirically the variables of human resource development and market uncertainty by using the moderating variable of effective organizational learning to increase corporate performance. Using data from 100 SMEs in two regencies in Central Java, and carrying out using AMOS 22, the results prove that effective organizational learning moderates human resource development and market uncertainty in their activities. These results prove that human resource development is needed to improve the effective organizational learning. This study provides the best insight into human resource development, especially in the SMEs. Some of the observed causes have been discussed in this study.