Empowering employees play essential role on increasing the productivity of any business units. In this paper, we present an empirical investigation to study the impact of spiritual on empowering employees of Payame Noor university in city of Tehran, Iran. The study uses two benchmark questionnaires to examine the hypotheses of this survey. There are seven sub-hypotheses associated with this study including the relationship between empowering employees from one side and vision, friendship, faith to work, being meaningful, organizational membership, organizational commitment and performance feedback. The results of implementation of structural equation modeling confirmed all sub-hypotheses except commitment.