The study aimed to identify the impact of supply chain integration through strategic performance and the mediating role of strategic vigilance in industrial companies. The Jordanian population is large and medium-sized, and the study population consists of medium and large-sized industrial companies. For hypothesis testing purposes the study and its model validity, Modeling Equation Structural Analysis (SEM) was used through the AMOS16 program. The study indicates that supply chain integration (strategic integration, internal integration, external integration) has an impact on strategic performance and response. The supply chain, as the results of the study indicated, shows that the response of the supply chain affects strategic performance. The study also found that the response of the supply chain mediates the impact of strategic vigilance on strategic performance. The study recommended working to raise the level of trust and honesty, commitment and attention to the interest of each party to the supply chain to maintain a good level of external integration of the supply chain and work to improve the level of supply chain response to markets and any changes that may occur in the market through corporate restructuring and streamlining working procedures.