The role of sustainability in supply chain is becoming critical due to increasing environment related problems and societal issues. Sustainable Supply Chain Management (SSCM) helps in reducing environmental degradation as well as social and economic implications. SSCM practices in Indian industries are in initial stage of implementation and industries find difficult to implement. Therefore, in present research, key enablers to initiate SSCM are recognized and analyzed. This research has recognized twelve enablers with the help of previous researches and expert survey. A Structural framework has been drawn with the use of Interpretive Structural Modeling (ISM) technique, to understand the relationship among the identified enablers and also to find the reliance of one on another. Further, MICMAC analysis has been employed for evaluating these identified enablers in accordance with Driving power and Dependence power. From ISM Methodology “Government policies and supportive systems” is found to be a key bottom enabler, which is important to implement the SSCM in Indian industries. For further future perspective, Decision Making Trial and Evaluation Laboratory (DEMATEL), can also be recommended for evaluation purpose. Present research may be helpful to find the importance of different enablers for successful implementation of SSCM in Indian industries.