The aim of this study is to explore factors affecting the adoption of blended learning strategy. Data was collected using a questionnaire consisting of 42 items, distributed to a random sample of 174 faculty members of Saudi Electronic University and Qassim University. IBM SPSS was used to conduct data analysis. Supporting research hypothesis indicates that student, institutional and learning variables had significant influences on the adoption of blended learning strategy. Considering the findings, it was concluded that the adoption of a blended learning strategy depends not only on the technological aspect of the learning process but also on people, i.e., students who are engaged in the process and motivated teachers who possess the required knowledge and skills. The most important implication of this research is that policy and decision makers in business educational schools are requested to consider factors that had a significant effect on the adoption of blended learning. In doing that, the research contributes to the blended learning knowledge via highlighting the key variables that encourage or hinder the adoption of blended learning strategy.