This research aims to improve a methodic for evaluation of economy’s competitiveness through theoretical-methodological substantiation, forming and calculation of integral indices of innovative technological competitiveness across the regions of a country. The relevance and indispensability of reinforcement of economy’s competitiveness on innovative technological foundations are also substantiated. Available methodical approaches in economic literature and competitiveness rankings and indices used by leading international economic organizations, namely in innovations and high technology domains, are generalized. Authors’ methodic of calculation of integral index of economy’s innovative technological competitiveness is suggested. Integral indicators of provision of innovative technological activity with resources, innovative technological activity and efficiency of innovative technological activity across regions (on the example of Ukraine) are calculated for 2009-2018; conclusions regarding the preconditions, capacity and availability of tendencies of innovative technological activity in oblasts (regions) of the country are made. The paper explains that each of the components of innovative technological competitiveness of the country’s economy had almost equal input in forming of its integral index – provision with resources, capacity and efficiency of innovative technological activity. In the first place, it is an additional argument in favor of the model’s reliability, and in the second place, it brings into the fore the importance of public policy in terms of improvement of resources maintenance of innovative and technologically active companies, boosting of innovative technological activity and increasing of its efficiency and contribution to general economic growth of the country. Strategic priorities of state policy of reinforcement of the economy’s innovative technological competitiveness are substantiated.