University autonomy is a necessary condition for the implementation of advanced university governance methods to improve and enhance the quality of training. This study aims to examine the influence of factors on linkage between public universities in the context of university autonomy in Vietnam. Using quantitative research methods, through multiplicative model analysis, with a scale of 528 samples being managers, experts, scientists at public universities which are then divided by different sectors. The results show that there are 5 factors that favorably influence the linkage between public universities in the context of autonomy with the order of influence defined as: Information sharing; Goal consensus; Financial resources; University brand values; Commitment. Based on the research findings, the authors propose a number of recommendations to strengthen the linkages between public universities in the context of university autonomy in Vietnam.