This study presents data on the development and research of cryogenic-vibration grinding process modes which would ensure an efficient grinding process of complex composite systems with a high degree of heterogeneity of components in their composition of products such as fluoroplast, bismuth oxide and tungsten carbide. The general regularities of low-temperature processing and grinding of non-degassed elastomers are established. A method has been tested that establishes the regularities of cryogenic grinding and ultrasonic homogenization of a complex mechanical system, the microstructure and dispersed compositions of the ground material have been determined.