This study was conducted to explore the relationship between e-learning service quality, e-trust, and e-loyalty in Vietnam, an emerging country. Data collected from 666 students were analyzed by exploratory factor analysis, confirmation factor analysis and linear model using SPSS 20.0 and AMOS 20.0 software. The results indicate that e-trust and e-learning service quality had positive impacts on e-loyalty. The study also shows e-learning service quality and e-learners' privacy and security affect e-trust positively. Besides, there is a positive and significance relationship among e-learners' privacy and security, e-learning support service quality, online course material quality and e-learning service quality. However, it is not yet possible to prove the role of online instructor quality in e-learning service quality.