This research is conducted to analyze and point out the relationship between environmental pollution and aquaculture development in the coastal areas in Vietnam. In this study, we use the binary Logit model (Y = 1/0) where the variable, Y, reflects the risks and losses in the household's aquaculture; and X is a vector of factors affecting the event. The results show that, among determinants, household's aquaculture experience (X1), the water pollution degree of the household (X4), intensive farming mode of the household (D1) influence household losses, while other variables such as educational attainment of the household head (X2) and farming area (X3) are not correlated with household losses. Based on the findings, some recommendations are given in the aspect that aquaculture households in the region to use new, more effective methods to protect the aquaculture environment in developing countries, including Vietnam.