Mobile e-learning within the education domain is now an integral part in education technology. However, there has been little discussion about the benefits and the challenges of the use of M-learning in the higher education system in KSA. Interviews were the primary instruments used for data collection in identifying the enabling and deterring the quality attributes of mobile e-learning use in the context in Saudi Arabia higher education. The research results revealed that learning content/information quality, system quality, service quality and instructional quality were the primary antecedents of Blackboard as a Learning Management System (LMS) in general and within the mobile devices, and this situation can enhance user’s attitude towards the use of E-learning. Data were analyzed and results were discussed. Recommendations were made based on the findings.