The objective of this study is to examine the role of HRM and supply chain to promote business performance (BP) sustainability in Thai textile firms. Meditating role of employee skills and raw material is examined. Therefore, the relationship between HRM, supply chain, employee skills, raw material and BP sustainability was examined. Population of the study is textile firms of Thailand. Employees of these textile firms were selected as respondents. 300 questionnaires were distributed among the textile firms of Thailand. Results of the study shows the positive role of HRM in BP sustainability. Better practices of HRM have the ability to promote BP sustainability. HRM has a positive role in employee skills development which further enhances BP sustainability. Moreover, supply chains in textile firms also play a major role to promote BP sustainability. Better supply chain increases the availability of raw material which causes BP sustainability.