This research aims to investigate the impact of adopting e-learning in an attempt to enhance higher thinking skills among students at the University of Jordan. In addition, we examine the relationship between e-learning and higher thinking skills and identify the effect of e-learning on higher thinking skills at the University of Jordan. The study examines the effect of using e-learning effectiveness and its effect on developing higher students’ thinking skills at the university level. The study also focuses on intellectual education for high-level thinking and the impact of the e-learning environment on a group of students at the University of Jordan. The target community for this study is undergraduate students at the University of Jordan, in Amman, Jordan. The resulted sample consists of 45 students. During the experiment, two research tools were used to analyze the relationship between the independent and dependent variables. The quantitative data are collected from the students’ perception analyzed using some statistical tests. The results of the research indicate that students could be helped to enhance higher-order thinking skills and maybe enriched by integrating an e-learning model into teaching and learning. There is also a positive relationship between e-learning and higher thinking skills at the University of Jordan. The experimental results of this study indicate several results, as the adoption of the e-learning model led to a significant improvement in the higher thinking skills of students. The e-learning model can remove many social and cultural barriers.