The global supply chain is facing risks and challenges that disrupt the supply chain and negatively affect performance. The high-quality cooperation between supply chain members is a useful solution to help limit risks and improve its performance. This study was conducted to demonstrate the relationship between collaboration, supply chain risk, and supply chain performance of organic agricultural products in Vietnam. Research data were collected from 162 enterprises producing organic agricultural products. Applying the structural equation modeling (SEM), the study has shown that supply chain risks negatively affect the supply chain performance of organic agricultural products. The close cooperation between members of the supply chain limits supply chain risks, thereby improving the efficiency of the supply chain of Vietnamese organic agricultural products.