This paper aims to shed light on whether the Merger & Acquisition (M&A) among several cases create values for Vietnam small and medium enterprises (SMEs). Using 48 months of actual data to compare the pre- and post- merger performance, the study evaluates the impacts of the M&A on business performance collected from HOSE stock exchange website. The result shows that out of 11 chosen key performance indicators (KPIs) and those selected firms only we have 2 KPIs with better results while 6 KPIs do not change and 3 KPIs are even worse after the M&A. In addition, the finding indicated that very few actions were implemented and hence unsurprisingly, the M&A outcomes did not really match with firms’ original expectations. From the theory and the actual results of the analysis, the study provides a number of practical areas that companies should focus on to increase the chance of success for their M&A.