An efficient one pot three-component synthesis of dihydropyrano[3,2-c] chromenes using ammonium metavanadate as catalyst
, Pages: 137-144
Balasaheb V. Shitole, Nana V. Shitole, Murlidhar S. Shingare and Gopal K. Kakde PDF (230 K)
Abstract: We report ammonium metavanadate catalyzed one-pot synthesis of 3,4-dihydropyrano[3,2-c]chromenes, from aldehydes, active methylene compounds malononitrile and 4-hydroxycoumarin in water:ethanol(1:1) under reflux. The attractive features of this process are mild reaction conditions, short reaction times, easy isolation of products, and excellent yields.
Keywords: Chromenes, Multi-component reaction, Ammonium metavanidate
A green chemoselective one-pot protocol for expeditious synthesis of symmetric pyranodipyrimidine derivatives using ZrOCl2.8H2O
, Pages: 145-154
Mehdi Rimaz, Hossein Mousavi, Mojgan Behnam and Behzad Khalili PDF (230 K)
Abstract: A convenient, highly efficient and time economic method has been described for the chemo- and regioselective synthesis of 5-aryloyl-1,3,7,9-tetraalkyl-2,8-dithioxo-2,3,8,9-tetrahydro-1H-pyrano[2,3-d:6,5-dˊ]dipyrimidine-4,6(5H,7H)-diones derivatives by one-pot two-component reaction of 1,3-diethyl-2-thiobarbituric acid or 1,3-dimethyl-2-thiobarbituric acid with substituted arylglyoxalmonohydrates using commercially available zirconium (IV) oxydichloride octahydrate (ZrOCl2.8H2O) as green Lewis acid catalyst. This method is associated with some attractive characteristics such as good selectivity, very short reaction time, high yield of products, cleaner reaction profile, no harmful by-product, cheap and environmental benign catalyst, simple experimental and work-up procedure. This procedure does not require solvent separation and purification steps such as column chromatography.
Keywords: Lewis-acid catalysis Green chemistry, Pyranopyrimidine, Arylglyoxal, One-pot synthesis
Feasibility study on the reaction of 1,4-diazabicyclo[2.2.2]octane (DABCO) with (L-Serine-L-Serine) and (L-Phenylalanine-L-Serine) diketopiperazines
, Pages: 155-164
Sitaram Bhavaraju PDF (230 K)
Abstract: This paper summarizes the reaction of DABCO with the enol tosylate derivatives made from (L-Ser-L-Ser) and (L-Phe-L-Ser) diketopiperazines (DKP’s). The reaction between DABCO and EE-di-tosylate (L-Ser-L-Ser) DKP (2), results in the isomerization of the serine di-tosylate from EE-2 to ZZ-2. This is the first direct example of the utility of DABCO as a reagent demonstrating the successful isomerization in a DKP derivative. The E-enol tosylate of (L-Phe-L-Ser) DKP (4) upon reaction with DABCO provided a unique bis-ylidiene product (5).
Keywords: 2,5-Diketopiperazine (DKP), Isomerization, 1,4-diazabicyclo[2.2.2]octane (DABCO), Enol tosylate, Bis-Ylidiene
FeCl3/SiO2 NPs as a robust and efficient catalyst for the synthesis of 2-aryl-5-methyl-2,3-dihydro-1H-3-pyrazolones
, Pages: 165-172
Esmaeil Afkhami and Javad Safaei-Ghomi PDF (230 K)
Abstract: A four-component reaction of phenylhydrazines, ethyl acetoacetate, aldehydes and β-naphthol has been achieved in the presence of FeCl3/SiO2 nanoparticles as a highly effective heterogeneous catalyst to produce 2-aryl-5-methyl-2,3-dihydro-1H-3-pyrazolones in good to excellent yields, short reaction times, mild reaction conditions and the employment of a cost-effective catalyst.
Keywords: FeCl3/SiO2 nanoparticles, Heterogeneous catalyst, Multi-component reactions, Pyrazolones
Synthesis, characterization and optical band gap of Pirochromite (MgCr2O4) Nanoparticles by Stearic Acid Sol-Gel Method
, Pages: 173-180
Ehsan Jafarnejad, Salah Khanahmadzadeh, Fatemeh Ghanbary and Morteza Enhessari PDF (230 K)
Abstract: Pirochromite (MgCr2O4) nanoparticles were successfully prepared in this study. During synthesis of the pirochromite nanoparticles, a sol-gel was prepared by using magnesium acetate and potassium dichromate as magnesium and chromium sources and by using stearic acid as the network. Infrared spectroscopy (FT-IR), X-ray diffraction (XRD), transmission electron microscope (TEM), scanning electron microscope (SEM), and energy-dispersive X-ray spectroscopy (EDX) were used for the elemental analysis, and diffuse reflectance spectroscopy (DRS) and vibrating sample magnetometer (VSM) were used in order to identify, provide a fuzzy diagnosis, and determine the size and morphology of the particles, as well as to analyze the optical and magnetic properties of the particles. The particle size of MgCr2O4 nanoparticles was observed to fall within a range of 39 nm–71 nm.
Keywords: Nanoparticles, Pirochromite, AB2O4, Sol-gel method, Fd3m
® 2016 GrowingScience.Com