The purpose of this study is to investigate the importance of factors that influence entrepreneurial intention among tourism undergraduate students in Vietnam. A research framework based on Theory of Planned Behavior (TPB) was proposed to understand the relationship between the TPB factors and entrepreneurial intention. Additionally, the relationship between entrepreneurship education and entrepreneurial intention was also investigated. A questionnaire was administered to a sample of 388 tourism undergraduate students at different universities across Vietnam. The partial least squares structural equation modeling (PLS-SEM) method was utilized to test the hypotheses of this research. The study findings show that subjective norms (SN), attitude toward entrepreneurship (AE), perceived behavioral control (PBC) and entrepreneurship education (EE) had direct effects on entrepreneurial intention (EI); however, perceived behavioral control had the strongest influence on entrepreneurial intention. The findings provide educators with insights into how to promote entrepreneurship activities among tourism undergraduate students in Vietnam through educational programs and training.