The objective of this paper is to assess the relationship between supply chain activities in retail businesses enterprises in Hanoi, Vietnam. The sample includes 312 retail business enterprises in Hanoi city. Using the analysis technology of PLS - SEM structure model, through Smart PLS 3.0 software, the results show that the activities of the retail supply chain in Hanoi were statistically significant where the effects were from 0.166 to 0.605 and the level of significance was 1%. Inventory does not have a statistically significant relationship with the supply chain management strategy of these retail businesses in Hanoi.