Due to various added advantages over the conventional material removal processes, non-traditional machining (NTM) processes have now been widely applied in different manufacturing industries. To achieve the desired response values, it is always recommended to operate these NTM processes at their optimal parametric settings. Various single response optimization techniques are already available to determine the optimal combinations of NTM process parameters for achieving maximum or minimum value of a single response. In this paper, a multivariate quality loss function approach is adopted for simultaneous optimization of responses for three NTM processes. It is observed that this approach outperforms the other multi-response optimization techniques, like desirability function, distance function and mean squared error methods with respect to the achieved re-sponse values. With modification of the corresponding objective function and constraints of the de-veloped non-linear programming problem, it can be effectively applied to any non-traditional as well as conventional machining process as a multi-objective optimization tool.