The study is conducted on the management factors affecting talent turnover in the banks’ credit card centers. For this purpose, the primary data are gathered from 73 respondents of credit card departments of banks listed in Pakistan Stock Exchange (PSX). Reliability test of questionnaire items, chi-square test, cross-tab, relational and regression analyses are used to analyze the interactions among variables. The study finds that work pressure and industrial development prospectus have positive linkage with dimensions of employee loyalty and talent turnover while compensation and benefits, promotion opportunities, management communication and work responsibilities are negatively associated with dimensions of employee loyalty and talent turnover. Conclusively, the study finds the following aspects as the main causes of talent turnover; loyalty imbalance, small promotion space and unstable working conditions. The prime cause of talent turnover in banks’ credit card businesses is loyalty imbalance. The study suggests banking firms to focus on trainings, recruitment and employees’ professional development with active characteristics of work to reduce the talent turnover rate. The banking firms should also provide opportunities to their employees to show their abilities and expertise.