The aim of writing this research article is to determine the influence of supply chain challenges on MSMEs performance, Supply chain integration on Micro, Small, and Medium Enterprises (MSMEs) performance, Management commitment to MSMEs performance, Supply chain integration on Supply chain performance. This research method is a quantitative survey, research data was obtained by distributing online questionnaires via social media. 700 questionnaires were distributed to MSMEs owners and of the 700 questionnaires distributed, 350 respondents or 50% responded as determined by the simple random sampling method. This research adopted a quantitative method with data analysis using Structural Equation Modeling (SEM) Partial Least Square (PLS) with SmertPLS software data processing tools. The questionnaire was designed using a Likert scale of 1 to 7. The stages of data analysis were validity, reliability and hypothesis testing. or significance. The results of data analysis show that supply chain challenges have a positive and significant influence on MSMEs performance, Supply chain integration has a positive and significant influence on MSMEs performance, Management commitment has a positive and significant influence on MSMEs performance, Supply chain integration has a positive influence and significant to supply chain performance. The novelty of this research is the creation of a relationship model of supply chain integration, management commitment, supply chain performance, supply chain challenges and MSMEs performance. The implication of this research is to encourage improvements in MSMEs performance, MSMEs managers must encourage improvements or implement challenges in the supply chain. Supply chain integration and management commitment. Supply chain management is not just about managing the flow of goods, but also a holistic business strategy that can create a competitive advantage. With a deep understanding of supply chain components, challenges and strategies, companies can ensure smooth operations and meet customer expectations in a dynamic and global business environment. Implementing best practices in supply chain management is the key to building a strong foundation for business success in an era of ever-growing globalization.