SMEs play a critical role for the economic growth of nations by providing the opportunity for individuals to develop their skills and to be self-employed. SMEs are flexible and are able to quickly acclimatize to the factors affecting supply and demand. In todays’ rapidly changing business environment, SMEs are faced with difficult challenges to effectively implement the practices that are frequently adopted by larger business rivals. This study will discuss the concept of entrepreneurial orientation, innovation performance, and learning orientation in the context of SMEs in Kuwait. This study assumes that Entrepreneurial Orientation has both direct and indirect impacts on Innovation Performance (IP) through the mediating role of learning orientation. This study used quantitative methods to investigate and test the hypothesis that the association of entrepreneurial orientation with innovation performance was mediated by learning orientation. The target population in the present study is the owners and CEOs of SMEs in Kuwait, and the stratified random sampling method was used to select 221 participants. This study used a structured questionnaire containing close ended questions to gather the data. The data was analyzed using the partial least square structural equation modelling (PLS-SEM). Results of the analysis show that learning orientation played a partial mediating role in the association of entrepreneurial orientation with innovation performance.