This study aims to explore the power of grit, personality, and creativity to enhance teacher’s professional competence with teaching efficacy mediation. A questionnaire collected the research data through the survey method. This research participant is 386 mathematics, and natural science teachers in Indonesia spread across four provinces (Jakarta, Banten, West Java, Riau) determined by accidental sampling. Data analysis uses path analysis supported by descriptive statistics. The results show that grit, personality, and creativity, had a significant effect on teacher’s professional competence, either directly or indirectly, mediating by teaching efficacy. Personality has a more dominant direct effect on teaching efficacy and professional competence than grit and creativity. Even personality also has an indirect impact on professional competence mediating by teaching efficacy better than grit and creativity. That means the existence of personality more critical than grit and creativity. Therefore, a fit research model about grit, personality, and creativity on teacher’s professional competence mediating by teaching efficacy was found based on data from teachers in Indonesia. This model can be discussed as a reference or discuss by researchers and practitioners in developing professional competence models.