In this paper, the relationship between political instability and sustainable supply chain management is examined within the context of Palestine. This is due to the fact that instable state has created a chaotic situation for manufacturers. This paper tends to this subject through quantitative measures from the perspective of employees. A number of 265 employees were selected in manufacturing organizations of Palestine, in which sus-tainable supply chain practices were found to be in the mindset of managers and have been shared with em-ployees and/or the practices are implemented within the firm. This study uses statistical analyses (ANOVA and Correlation analysis) alongside construct reliability and factor loadings to test proposed hypotheses. Results of the analysis show a significant negative effect from political instability and its dimension upon sustainable supply chain management practices and their implementation that is perceived by the employees. Contributions of this papers are threefold as the literature lacks direct examination of current factors, instable countries such as Palestine have not been examined in terms of sustainable supply chain, and managers can benefit from importance of various factors of sustainable practices of supply chain.