The rapid technological changes in recent decades have created tremendous motivations among entrepreneurs to offer value added products and services. The complicated relationships between technology and innovation have caused to create the innovation management. Therefore, the key prominence of innovation in global village is to design new plans to manage and improve the innovation so that they could continue aiming at their superior national-organizational goals along with their growth and improvement path within their strategic plans. Many countries are interested in comparing themselves with other societies for enhancing their entrepreneurial awareness in an approximate rate and exploit their successful and positively affecting on development of the entrepreneurship innovation-management experiences and policies. In this research, the impact of each determinant of innovation management influencing on entrepreneurial activities in Iran and the members of Global Entrepreneurship Monitor between 2008 and 2011 is studied and evaluated using the structural equations.