The satellite structural mass is considered a crucial parameter during the process of satellite structural design. Sandwich structures acquire a considerable role in minimizing such mass while maintaining structural integrity. This article discusses the structural configuration, design, and analysis of a small satellite. A small Earth remote sensing satellite is chosen from the published data as a case study. Its structural design configuration is of a rectangular box that is based upon metallic alloys. Through a comprehensive study, the most suitable design configuration for the given mission is selected. A contribution has been made in developing a novel hexagonal primary structure that is based upon Aluminum honeycomb sandwich panels. The satellite configuration process and structural design procedure are thoroughly presented. The finite element modeling of honeycomb sandwich panels according to sandwich theory is introduced. Such modeling is validated numerically in comparison with published data. The analysis process is implemented using finite element analysis considering the loads during the ground and launch phases. The proposed structural design results in a significant mass reduction of 15% when compared with the baseline case study.